Background: Health-related quality of life (HRQL), life satisfaction, living conditions, patients' attitudes towards life and death, expectations, beliefs and unmet needs are all poorly understood aspects associated with patients receiving invasive home mechanical ventilation (HMV) following ICU treatment and unsuccessful weaning. Therefore, the present study aimed to assess (1) HRQL, (2) life satisfaction and (3) patients' perspectives on life and death associated with invasive HMV as the consequence of unsuccessful weaning.
Results: Patients undergoing invasive HMV with full technical supply and maximal patient care were screened over a 1-year period and assessed in their home environment.
Background And Objective: Continuous partial pressure of carbon dioxide (PCO ) assessment is essential for the success of mechanical ventilation (MV). Non-invasive end-tidal PCO (PetCO ) and transcutaneous PCO (PtcCO ) measurements serve as alternatives to the gold standard arterial PCO (PaCO ) method, but their eligibility in critical care is unclear.
Methods: The present study therefore performed methodological comparisons of PaCO versus PetCO and PtcCO , respectively, in weaning patients receiving invasive MV via tracheal cannulas.
Introduction: A restful sleep is essential for regenerative processes and remains crucial for patients recovering from stressful periods in the intensive care unit. The current study aimed to assess sleep quality in critically ill patients receiving invasive mechanical ventilation within a specialized weaning unit in hospital.
Methods: Tracheotomized subjects undergoing prolonged weaning from mechanical ventilation were included in the study.
Background: The number of patients with invasive home mechanical ventilation (HMV) following unsuccessful weaning is steadily increasing, but little is known about the living conditions and health-related quality of life (HRQL) in these patients.
Objectives: To establish detailed information on living conditions and HRQL in patients with invasive HMV.
Methods: The Severe Respiratory Insufficiency Questionnaire (SRI) was used to measure specific HRQL aspects in addition to patient interviews on individual living conditions during home visits.
Background: Correct measurement of PO₂ and PCO₂ is essential to establish appropriate therapy such as long-term oxygen therapy (LTOT) in patients suffering from respiratory failure.
Objectives: We aimed to compare common invasive and noninvasive methods for assessing blood gas components for spot check analysis.
Methods: Arterial (PaO₂, PaCO₂) and capillary blood gas (PCBGO2, PCBGCO2) measurements were taken consecutively in a randomized order and were compared with noninvasive measurements obtained from the transcutaneous monitoring of PO₂ and PCO₂ (PtcOv, PtcCO₂, sensor-temperature 44°C).
The relationship between an elevated partial pressure of carbon dioxide (Pco2) and reduced alveolar ventilation resulting from respiratory failure primarily affecting the respiratory pump was first reported during the 1952 Copenhagen polio epidemic. Several methods for Pco2 estimation, such as blood gas analyses, capnography, and transcutaneous Pco2 measurements, have since been developed to assess alveolar ventilation. The clinical setting in which CO2 measurement is valuable includes acute and chronic respiratory failure, transport, cardiopulmonary resuscitation, patient-controlled analgesia, and procedural sedation.
View Article and Find Full Text PDFBackground: When supplemental oxygen is added to noninvasive ventilation using a non-ICU ventilator, it is usually introduced with a preset flow into the circuit near the ventilator; however, the impact of different CO2 exhalation systems and leaks on the actual FIO2 and gas exchange has not been elucidated.
Methods: In a randomized, open-label, 4-treatment (2-by-2), 4-period crossover design, 4 daytime measurements (60 min each) were performed in 20 subjects receiving home mechanical noninvasive ventilation plus supplemental oxygen (≥ 2 L/min) inserted near the ventilator: active valve circuit or leak port circuit with or without artificial leakage (4 mm inner diameter). Oxygen concentration near the ventilator, oxygen concentration at the mask, and blood gases were measured.