Validation of 6 min step test and 4-m gait speed in children: A randomized cross-over study.

Introduction: Even if 6-min walking test (6MWT) is the criterion standard for functional exercise performance evaluation, new field tests are required as practical alternative. This study aims to establish the validity of the 6-min step test (6MST) and the 4-m gait speed (4MGS) in children.

Method: It is a randomized cross-over trial.

Infusion set characteristics such as antireflux valve and dead-space volume affect drug delivery: an experimental study designed to enhance infusion sets.

Background: The ability of an infusion set to deliver a specific amount of drug to the patient can be directly related to the presence of an antireflux valve and dead-space volume. In this study we quantified separately the impact of these 2 components on drug delivery.

Methods: Various infusion sets were assessed differing in length, in dead-space volume, and with or without an antireflux valve.

Impact of multiaccess infusion devices on in vitro drug delivery during multi-infusion therapy.

Background: Multiaccess infusion sets allow multiple simultaneous infusions but may induce interference in drug delivery resulting from large variations in the delivery rate of potent drugs. In this study, we sought to understand the influence of multiaccess infusion device properties (dead space volume and antireflux valve [ARV]) on drug delivery during multi-infusion therapy.

Methods: Infusion sets differing in length, dead space volume, and presence of an ARV were assessed.