Publications by authors named "Sophie Cramer-Benjamin"

Article Synopsis
  • The study investigates synaptic density in autistic adults using positron emission tomography (PET) and synaptic vesicle glycoprotein 2A (SV2A) as a marker.
  • Results show that autistic individuals exhibit a 17% lower synaptic density across the whole cortex compared to non-autistic peers, with significant deficits in various brain regions, especially the prefrontal cortex.
  • The findings suggest that lower synaptic density is associated with increased autistic features, pointing to a potential molecular basis for autism that requires further exploration.
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How do children form beliefs about the infinity of space, time, and number? We asked whether children held similar beliefs about infinity across domains, and whether beliefs in infinity for domains like space and time might be scaffolded upon numerical knowledge (e.g., knowledge successors within the count list).

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Importance: Face processing is foundational to human social cognition, is central to the hallmark features of autism spectrum disorder (ASD), and shapes neural systems and social behavior. Highly efficient and specialized, the face processing system is sensitive to inversion, demonstrated by reduced accuracy in recognition and altered neural response to inverted faces. Understanding at which mechanistic level the autistic face processing system may be particularly different, as measured by the face inversion effect, will improve overall understanding of brain functioning in autism.

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