Publications by authors named "Sophie Clark"
Memory loss and dementia are among older adults' greatest health fears. This article provides insight into new developments to help delay the onset of dementia, to treat dementia in its earliest stages, and to manage behavioral problems that occur in persons with dementia. Urinary incontinence (UI) is another common problem in older adults that has a major impact on quality of life.
View Article and Find Full Text PDFBackground: People from ethnic minority groups are disproportionately affected by COVID-19, less likely to access primary health care, and have reported dissatisfaction with health care. Although the prevalence of long COVID in ethnic minority groups is unclear, such populations are underrepresented in long-COVID specialist clinics and long-COVID lived-experience research, which informed the original long-COVID healthcare guidelines.
Aim: To understand the lived experiences of long COVID in people from ethnic minority groups.
Background: Post-acute sequelae of SARS-CoV-2 (PASC) describes a syndrome of physical and cognitive decline that persists after acute symptoms of infection resolve. Few studies have explored PASC among nursing home (NH) residents.
Methods: A retrospective cohort study was conducted at two NHs in Michigan.
Objectives: Although both high-frequency and burst spinal cord stimulation (SCS) have shown improved efficacy and patient satisfaction compared with conventional tonic stimulation, there are limited data directly comparing the two. This study aimed to compare both high-frequency 10,000 Hz and burst SCS in the same patients in terms of pain relief and satisfaction in those with axial back pain with or without leg pain.
Materials And Methods: This prospective, single-blind, randomized controlled trial was conducted at an outpatient pain clinic within an academic medical center.
Article Synopsis
- Alzheimer's disease (AD) risk is influenced by genetics, specifically the apolipoprotein E (APOE) genotype, and the study investigates its impact on a mouse model's olfactory system.* -
- The research utilized various methods including RNA-Seq and immunohistochemistry, revealing differences in gene expression between mice with APOE E3 and E4 alleles at 6 months, indicating development differences but no immediate effect on cell respiration.* -
- Findings suggest that while olfactory neuron apoptosis remains consistent at 6 months, it increases in E4 mice by 10 months, highlighting the olfactory epithelium's potential as a model to study how APOE alleles influence age-related AD progression
Introduction: The National Early Warning Score (NEWS) aids the early recognition of those at risk of becoming critically ill. NEWS has been recommended for use by ambulance services, but very little work has been undertaken to date to determine its suitability. This paper examines whether a prehospital NEWS derived from ambulance service clinical observations is associated with the hospital ED disposition.
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