Publications by authors named "Sophie Campana"

Background And Objective: Muscle fat infiltration (MFI) can be seen in several pathologies of various origin including neuromuscular, endocrinological, or musculoskeletal etiologies. Its evaluation is possible through medical imaging, especially MRI, using qualitative or quantitative methods. This paper is an overview of the techniques used to evaluate MFI in different pathologies.

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Article Synopsis
  • The study investigates the impact of a compressive follower preload on the biomechanics of the cervical spine through both in vitro cadaver tests and numerical simulations.
  • Results showed that applying a 50-N follower load altered spinal motion, increasing cervical lordosis and changing ranges of motion (ROM) during flexion/extension while decreasing it during axial rotation and lateral bending.
  • Findings from the finite element analysis indicated only minimal changes in ROM with a 50-N load, revealing that while intradiscal pressures increased, overall motion was not significantly affected compared to intact conditions.
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Minimally invasive surgeries aiming to restore fractured vertebral body are increasing; therefore, our goals were to create a 3D vertebra reconstruction process and design clinical indices to assess the vertebral restoration in terms of heights, angles and volumes. Based on computed tomography (CT)-scan of the vertebral spine, a 3D reconstruction method as well as relevant clinical indices were developed. First, a vertebra initial solution requiring 5 min of manual adjustments is built.

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Background: The purpose of the study was to report radiological outcomes after total disc replacement (TDR) in the cervical spine through a 24 months follow-up (FU) prospective study with a special focus on sagittal alignment and kinematics at instrumented and adjacent levels.

Materials And Methods: Thirty-two patients, who sustained one-level TDR with a ball-and-socket arthroplasty (Discocerv(™) implant, Scient'x/Alphatec Spine, USA) were consecutively included in the study. Clinical (visual analogical scale and neck disability index) and radiological parameters were measured preoperatively and postoperatively at 3/6 months, 1-year and 2-year FU.

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Article Synopsis
  • The study aimed to analyze the movement and pressure characteristics of the cervical spine after different surgical interventions: 1-level and 2-level total disc replacements (TDR), anterior cervical arthrodesis (ACA), and hybrid constructs.
  • Twelve human cadaveric spines were tested under controlled conditions to compare how these surgeries affected range of motion (ROM) and pressures at adjacent disc levels.
  • The findings indicated that while TDR partially restored spine movement, it provided better mechanical outcomes than traditional arthrodesis, particularly by reducing stress on adjacent segments and limiting their contribution to overall spinal motion.
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