APTC-EC-2A: A Lytic Phage Targeting Multidrug Resistant Planktonic Cells and Biofilms.

() are common bacteria that colonize the human and animal gastrointestinal tract, where they help maintain a balanced microbiome. However, some strains are pathogenic and can cause serious infectious diseases and life-threatening complications. Due to the overuse of antibiotics and limited development of novel antibiotics, the emergence of antibiotic-resistant strains has threatened modern medicine, whereby common infections can become lethal.

Preclinical Development of a Bacteriophage Cocktail for Treating Multidrug Resistant Infections.

A () airway infection is one of the predominant causes contributing to the high morbidity and mortality rates in cystic fibrosis (CF) patients. The emergence of antibiotic resistant strains has led to an urgent need for new therapeutic approaches. Bacteriophages (phages) are viruses that can infect and lyse specific bacteria, providing a potential alternative approach in targeting antibiotic-resistant strains.