Publications by authors named "Sophie Blanchi"

Article Synopsis
  • Francisella tularensis endocarditis is a rare infection that's tough to diagnose, with only a handful of cases documented.* -
  • The report discusses two new cases caused by the subsp. holarctica strain, highlighting their positive outcomes through antibiotic treatment and valve replacement surgery.* -
  • Effective treatment typically involves ciprofloxacin and gentamicin, alongside surgical intervention when required, with suspicion of the infection guided by local epidemiology and patient exposure.*
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Objectives: The emergence of SARS-CoV-2 variants raised questions about the extent to which vaccines designed in 2020 have remained effective. We aimed to assess whether vaccine status was associated with the severity of Omicron SARS-CoV-2 infection in hospitalized patients.

Methods: We conducted an international, multi-centric, retrospective study in 14 centres (Bulgaria, Croatia, France, and Turkey).

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Article Synopsis
  • * A total of 955 patients were analyzed, revealing that vaccinated individuals were older, more male-dominated, and had more health issues, but experienced less severe Covid-19 outcomes compared to unvaccinated patients.
  • * Vaccination significantly reduced the likelihood of requiring intensive care, needing oxygen, and the risk of death, emphasizing its importance in managing severe cases of COVID-19.
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  • The study aims to assess the prevalence of measles antibodies among adults living with HIV in France, focusing on those born after the measles vaccine was introduced.
  • Conducted between April 2019 and April 2020, it involved 648 participants, finding that 87.2% had positive measles serology, but only 81.8% of vaccinated individuals tested positive.
  • Key factors associated with a lack of measles antibodies included younger age, being born in France, and having fewer social vulnerabilities, highlighting the need for better vaccination tracking in this population.
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Background: Humoral response against sudden acute respiratory syndrome coronavirus 2 (SARS-CoV-2) after two doses of BNT162b2 (Pfizer-BioNTech) has been proven to be less intense in maintenance dialysis patients as compared with healthy subjects, leading the French authorities to recommend a third injection in this population. Here we investigated the response to the third injection in two cohorts of haemodialysis (HD) patients.

Methods: Data from two prospective observational cohorts were collected.

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Introduction: Patients on dialysis (HDPs) are a category at high risk from COVID-19 and thus a high-priority group for vaccination. COVID-19 vaccine hesitancy has been a concern since the availability of the first vaccine. The objective of this study was to determine hesitancy rates and factors associated with hesitancy toward COVID-19 vaccination in HDP.

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  • The study aimed to evaluate French General Practitioners' (GPs) practices regarding catch-up vaccinations for migrants, highlighting the incomplete vaccination status often encountered in this population.
  • Conducted via an online questionnaire, the research involved responses from 216 GPs, revealing a majority consider their knowledge of migrant vaccination average and generally do not administer more than two vaccines in a single visit.
  • Findings indicated variations in practices among GPs, with private practitioners more likely to follow full vaccination schedules, and raised concerns over the reliability of migrants' self-reported vaccination status, prompting a need for standardized guidelines.
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  • In this study, researchers wanted to find a better way to help kids feel less pain during needle procedures, comparing a new device called Buzzy with the usual lidocaine patches.
  • They tested both options on children aged 4-15 at vaccination centers in France, where kids could use either the Buzzy device, which provides cold and vibration, or the lidocaine patch that numbs the area.
  • The results showed that kids using Buzzy reported their pain scores, and the study aimed to see if Buzzy worked just as well as the lidocaine patch.
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In France, diphtheria tetanus and inactivated polio vaccine (DT-IPV) coverage and immunization are insufficient in the elderly and decrease with age. The principal objective of this study was to assess the impact of a strategy of catch-up DT-IPV vaccination during hospitalization in people over the age of 65 years in central France (the Sarthe region). We performed a prospective, single-center, cluster-randomized study (four hospital wards).

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Postexposure prophylaxis (PEP) prevents human rabies and is accessible in Cambodia principally in Phnom Penh, the capital. Timely, affordable access to PEP is a challenge for the mainly rural population. We aimed to identify districts independently associated with PEP noncompletion to position frontline vaccination centers.

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Aspergillus terreus, a saprophytic fungus, is recognized as an emerging pathogen responsible for various infections in human beings. However, bone and joint involvement is uncommon. We report a rare case of A.

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Synopsis of recent research by authors named "Sophie Blanchi"

  • Sophie Blanchi's research focuses on infectious diseases, particularly exploring the effects of vaccinations, the diagnosis and management of rare infections, and the implications for vulnerable populations, including those with comorbidities.
  • Her recent articles include case studies on rare infections like Francisella tularensis endocarditis and the examination of vaccination impacts on symptoms and severity in hospitalized COVID-19 patients, highlighting the need for continued vaccine effectiveness monitoring.
  • Blanchi also investigates public health issues, such as vaccine hesitancy in dialysis patients and immunization strategies for migrants, emphasizing the importance of catch-up vaccinations and healthcare access for underserved populations.