Publications by Sophie A S Lawrence

Publications by authors named "Sophie A S Lawrence"

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Phospholipids Differentially Regulate Ca Binding to Synaptotagmin-1.

Sophie A S Lawrence Carla Kirschbaum Jack L Bennett Corinne A Lutomski Tarick J El-Baba

ACS Chem Biol

April 2024

Synaptotagmin-1 (Syt-1) is a calcium sensing protein that is resident in synaptic vesicles. It is well established that Syt-1 is essential for fast and synchronous neurotransmitter release. However, the role of Ca and phospholipid binding in the function of Syt-1, and ultimately in neurotransmitter release, is unclear.

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