Loeys-Dietz syndrome (LDS) is a connective tissue disorder with features including, but not limited to, aortic dissections, skeletal abnormalities, and craniofacial defects. However, considering its relatively recent discovery, there are still many unknowns about LDS. The extent of a connective tissue disorder like LDS is yet to be defined throughout the various organ systems, including the gastrointestinal system.
View Article and Find Full Text PDFCooking at home is a critical survival skill. We propose a new cooking assistance system in which a user only needs to wear an all-in-one augmented reality (AR) headset without having to install any external sensors or devices in the kitchen. Utilizing the built-in camera and cutting-edge computer vision (CV) technology, the user can direct the AR headset to recognize available food ingredients by simply looking at them.
View Article and Find Full Text PDFPurpose: To review published literature assessing clinical outcomes and complication rates of single incision fasciotomy in fractures of the lower leg.
Methods: We searched PubMed and EMBASE for articles published through July 5, 2021, using the terms "single incision fasciotomy", "acute compartment syndrome of the limbs", "compartment syndrome fasciotomy", and "(compartment syndrome fasciotomy) AND (incision)". The inclusion criteria were studies of Level I to IV evidence in English, published in 1970 or later, involving human subjects, reporting clinical outcomes of single incision fasciotomy performed in cases of acute compartment syndrome in lower leg fractures, including at least 1 patient.
J Exp Psychol Hum Percept Perform
August 2021
Is it possible that silent reading rate is the same as the most efficient listening rate? The hypothesis has been formulated in the past, but never got much traction because silent reading is almost twice as fast as typical speech. On the other hand, several studies have shown that listening comprehension retains high quality for spoken materials presented at speeds up to 275 words per minute (wpm), and a recent meta-analysis has also shown that reading rate is lower than often thought: 240-260 wpm on average. To address the question above, we ran a new study specifically comparing spontaneous silent reading rate with comprehension of speech presented at different rates within the same participants and using matched texts.
View Article and Find Full Text PDFNeurol Neuroimmunol Neuroinflamm
January 2021
Objective: To determine the long-term safety and efficacy of repeated intrathecal (IT) administration of autologous mesenchymal stem cell-derived neural progenitors (MSC-NPs) in patients with progressive MS by evaluating subjects 2 years after treatment.
Methods: Twenty subjects were enrolled as part of a phase I, open-label single-arm study of 3 IT injections of MSC-NPs spaced 3 months apart. Subjects were evaluated for adverse events and disability outcomes including the Expanded Disability Status Scale (EDSS) and the timed 25-foot walk (T25FW).
A global priority for the behavioural sciences is to develop cost-effective, scalable interventions that could improve the academic outcomes of adolescents at a population level, but no such interventions have so far been evaluated in a population-generalizable sample. Here we show that a short (less than one hour), online growth mindset intervention-which teaches that intellectual abilities can be developed-improved grades among lower-achieving students and increased overall enrolment to advanced mathematics courses in a nationally representative sample of students in secondary education in the United States. Notably, the study identified school contexts that sustained the effects of the growth mindset intervention: the intervention changed grades when peer norms aligned with the messages of the intervention.
View Article and Find Full Text PDFObjective: To evaluate the implementation of a delayed cord-clamping protocol at an academic medical center, and its short-term associations on term neonates.
Methods: This was a retrospective cohort study of women aged 18 years or older delivering a term neonate at an academic medical center before and 5-7 months after implementation of a universal delayed cord-clamping protocol (October-December 2015 and October-December 2016, respectively). The primary outcome measure was the mean peak neonatal transcutaneous bilirubin level, with secondary outcome measures including mean initial transcutaneous bilirubin levels, mean serum bilirubin levels, number of serum bilirubin levels drawn, incidence of clinical jaundice, and phototherapy.
This study is to review published cases of peripartum cardiomyopathy (PPCM) treated with bromocriptine and outline pros and cons of the treatment strategy. Data were collected from PubMed/MedLine, ClinicalTrials.gov; the years 2007 to 2018 were searched for English-language articles.
View Article and Find Full Text PDFA scalable method for fabricating architected materials well-suited for heat and mass exchange is presented. These materials exhibit unprecedented combinations of small hydraulic diameters (13.0-0.
View Article and Find Full Text PDFRationale: Ca(V)1.2 channels are essential for excitation-contraction coupling in the cardiovascular system, and alternative splicing optimizes its role. Galectin-1 (Gal-1) has been reported to regulate vascular smooth muscle cell (VSMC) function and play a role in pulmonary hypertension.
View Article and Find Full Text PDFNonlinear feedback interactions have been shown to amplify contrast due to small differences in resonance frequency arising from microscopic susceptibility variations. Determining whether the selectivity of feedback-based contrast enhancement for small resonance frequency variations remains valid even in the presence of macroscopic field inhomogeneity is important for transitioning this new methodology into in vivo applications in imaging systems with lower field strengths and poorer homogeneity. This work shows that contrast enhancement under the radiation damping (RD) feedback field is sensitive to microscopic intravoxel frequency variations.
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