The role of the microbiome in immune checkpoint inhibitor colitis and hepatitis.

Immune checkpoint inhibitors have revolutionised management for a variety of different types of malignancies. However, gastrointestinal adverse effects, in particular colitis and hepatitis, are relatively common with up to 30 % of patients being affected. The gut microbiome has emerged as a potential contributor to both the effectiveness of immune checkpoint inhibitors and their side effects.

Correction of Lying Ear and Aesthetic Modification of Helix and Ear Lobule With Hyaluronic Acid Filler Injection: Experience in Chinese Patients.

Background: Large and long ears are regarded as symbols of wealth and health in East Asian culture, and people with lying ears often want their ears to be more exposed and prominent. Surgeries to correct lying ears have been documented.

Objectives: The aim of this study was to report the correction of lying ears and the aesthetic modification of helix and ear lobule with hyaluronic acid (HA) injections.

Workplace chemical and toxin exposures reported to a Poisons Information Centre: a diverse range causing variable morbidity.

Objective: The aim of this study is to determine the period prevalence, nature and causes of workplace chemical and toxin exposures reported to the Victorian Poisons Information Centre (VPIC).

Patients And Methods: All cases classified as 'workplace: acute' when entered into the VPIC database (June 2005-December 2013) were analysed. Data were collected on patient sex, the nature of the chemical or toxin, route of exposure and season.

Non-medical needs of older patients in the emergency department.

Aim: To determine the non-medical needs of older patients in the emergency department (ED).

Methods: We undertook a cross-sectional survey of three age groups (50-64, 65-79, 80+ years) using a self-administered questionnaire with five response options (strongly agree-strongly disagree) for 31 items.

Results: There were 548 patients enrolled.

Variables associated with parent satisfaction with their child's pain management.

Objective: The provision of 'adequate analgesia' (which reduces the pain score by ≥2 and to <4 [0-10 scale]) is significantly associated with high levels of satisfaction with pain management among adult patients. We aimed to determine the variables (including 'adequate analgesia') associated with parent satisfaction with their child's pain management.

Methods: We undertook an observational, pilot study in a mixed, metropolitan ED.

Results of pancreatic resection associated with portal vein resection in an Australian tertiary care centre.

Background: Portal vein resection (PVR) with pancreatectomy is now accepted practice in cases with involvement by tumour. We present our experience of this procedure with particular emphasis on morbidity and survival.

Methods: A retrospective case-control analysis of a prospectively maintained database between 2004 and 2012 was undertaken.