Red cell alloimmunization is associated with development of autoantibodies and increased red cell transfusion requirements in myelodysplastic syndrome.

Up to 90% of patients with a myelodysplastic syndrome require red blood cell transfusion; nevertheless, comprehensive data on red cell alloimmunization in such patients are limited. This study evaluates the incidence and clinical impact of red cell alloimmunization in a large cohort of patients with myelodysplastic syndrome registered in the statewide South Australian-MDS registry. The median age of the 817 patients studied was 73 years, and 66% were male.

Blood transportation for medical retrieval services.

Introduction: Medical retrieval services resuscitate and retrieve the critically ill and injured. Lifesaving treatment includes the transfusion of red blood cells (RBCs). To ensure patient safety and maximum therapeutic benefit for the patient, the transportation of RBCs for transfusion must occur under optimal conditions.