Publications by authors named "Sophia Cornew"
Increasing Clinical Trial Participation of Black Women Diagnosed with Breast Cancer.
J Racial Ethn Health Disparities
June 2024
Despite racial disparities in breast cancer mortality, Black women remain underrepresented in clinical trials. In this mixed methods research, 48 Black women were engaged via focus group discussions and in-depth interviews to better understand the lived experience of women with breast cancer. The results of this qualitative study informed the development of a subsequent online survey to identify barriers, motivators, and other factors that influence decision-making by Black women diagnosed with breast cancer when considering clinical trial participation.
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- A study examined health-related quality of life (HRQoL) for patients with cholangiocarcinoma (CCA), revealing limited data on how experimental therapies impact patients' well-being.
- Of the 208 patients surveyed, those in clinical trials or receiving targeted therapy experienced similar physical and emotional health as those who weren't, but reported greater financial burden.
- The findings suggest that while new therapies do not harm overall well-being, they are associated with higher costs and limited accessibility, emphasizing the need to improve access and reduce financial strain on patients.
The development of JFH1 based intergenotypic recombinants that exploit the unique replication characteristics of JFH1 has made it possible to study infectious hepatitis C virus (HCV) encoding the structural genes of additional HCV genotypes. To facilitate the study of 1b structural proteins, we aimed to develop a robust 1b/2a chimera encoding a humanized Renilla luciferase reporter gene (1b/2a hRluc). The unadapted genome replicated efficiently but produced very low titers of infectious virus.
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