Publications by authors named "Soon Ruey"
Background: The rising number of newborns requiring neonatal intensive care unit (NICU) care poses immediate threats to their health and places emotional and financial burdens on families and healthcare systems. This study investigates the direct effect of maternal short stature on NICU admission in Sabah, Malaysia.
Methods: A longitudinal study at Hospital Wanita Dan Kanak-Kanak Sabah (HWKKS) from 2018 to 2022 included 254 Malaysian women with singleton pregnancies and neonates born after the 37th week, excluding significant disorders, smoking/alcohol use, fetal death, and malformations.
Article Synopsis
- Incidence rates of respiratory syncytial virus-associated lower respiratory tract illness (RSV-LRTI) in infants were assessed in low- and middle-income countries (LMICs) as existing data was limited.
- The study followed 2,094 infants from 10 LMICs over one year, using surveillance and testing to identify cases during the COVID-19 pandemic.
- Results indicated a low incidence of RSV-LRTI (1.5% of infants) and all-cause lower respiratory tract infections, likely influenced by reduced viral activity during the pandemic.
Article Synopsis
- A study in six Asian countries evaluated the real-world impact of dienogest treatment on health-related quality of life (HRQoL) in women with endometriosis, enrolling 887 participants with endometriosis-associated pelvic pain (EAPP).
- Results indicated significant improvements in HRQoL scores, especially in pain levels and feelings of control, with the most significant changes observed at 6 and 24 months after starting treatment.
- While many patients and doctors expressed satisfaction with dienogest, common side effects included bleeding irregularities and amenorrhea, with nearly 40% experiencing treatment-emergent adverse events.
Background: Dienogest has been shown to substantially improve endometriosis-associated symptoms such as debilitating chronic pelvic pain, and in turn, health-related quality of life (HRQoL). To date, there is no data on patient-reported outcomes reflecting the real-world practice in Asia where endometriosis is a relevant health, social and economic burden. This non-interventional, multi-center, prospective study aims to investigate the influence of dienogest on HRQoL.
View Article and Find Full Text PDFPurpose: To comparatively evaluate the results of a 2-dose human papillomavirus (HPV) vaccination programme with the AS04-adjuvanted HPV16/18 vaccine (AS04-HPV-16/18v) or HPV-6/11/16/18 vaccine (4vHPVv), in addition to cervical cancer (CC) screening, in Malaysia. Methods: A lifetime Markov model replicating the natural history of HPV in 13-year-old girls was adapted to Malaysia to assess the impact of vaccination on pre-cancerous lesions, genital warts and CC cases, CC deaths, quality-adjusted life years (QALYs), and costs from the perspective of the Malaysian Ministry of Health. Vaccine effectiveness was based on efficacy and HPV type distribution.
View Article and Find Full Text PDFObjective: Independent, prospective, multicenter, hospital-based cross-sectional studies were conducted across 5 countries in Asia, namely, Malaysia, Vietnam, Singapore, South Korea, and the Philippines. The objectives of these studies were to evaluate the prevalence of human papillomavirus (HPV) types (high risk and others including coinfections) in women with invasive cervical cancer (ICC) and high-grade precancerous lesions.
Methods: Women older than 21 years with a histologic diagnosis of ICC and cervical intraepithelial neoplasia [CIN 2 or 3 and adenocarcinoma in situ (AIS)] were enrolled.
To determine why HPV vaccination uptake is low in Asia, we surveyed attitudes, knowledge and communication about cervical cancer and HPV vaccination amongst 480 physicians and 1617 randomly selected urban mothers who could afford HPV vaccines in Korea, Malaysia, Taiwan and Thailand. HPV vaccine rejection by mothers was linked with poor knowledge and low perceptions of self-relevance. Physicians' likelihood of raising the subject and/or recommending vaccination was linked to how proactively they advocate preventive health, their attitude to the subject's sensitivity and their knowledge levels.
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