This study aimed to synthesize phenytoin (PHT)-loaded water chestnut starch-based biomaterials and evaluate their drug release kinetics for use in transdermal drug delivery systems for antiepileptic therapy. Hierarchical microparticles (HMPs) extracted from human hair were also used to improve the PHT release efficiency. The physicochemical characteristics of PHT, HMPs, and the prepared biomaterials were evaluated by physical properties, antimicrobial activities, FE-SEM, FT-IR, XRD, H NMR, and C CPMAS solid-state NMR.
View Article and Find Full Text PDFThe use of powered activated carbon is often limited by inconsistent particle sizes and porosities, leading to reduced adsorption efficiencies. In this study, we demonstrated a practical and environmentally friendly method for creating a 3D graphene nanostructure with highly uniform ultramicropores from wood-based biomass through a series of delignification, carbonization, and activation processes. In addition, we evaluated the capture characteristics of this structure for CO, CH, and N gases as well as its selectivity for binary-mixture gases.
View Article and Find Full Text PDFFoam cell formation plays a pivotal role in atherosclerosis-associated cardiovascular diseases. Bioactive peptides generated from marine sources have been found to provide multifunctional health advantages. In the present study, we investigated the anti-atherosclerotic effects of LLRLTDL (Bu1) and GYALPCDCL (Bu2) peptides, isolated from ark shell protein hydrolysates by assessing their inhibitory effect on oxidized LDL (oxLDL)-induced foam cell formation.
View Article and Find Full Text PDFCaptopril (CTP) is an oral drug widely used to treat high blood pressure and congestive heart failure. In this study, CTP-incorporated biomaterials for antihypertensive therapy were synthesized from chitosan, carboxymethyl cellulose, and plasticizers. The physicochemical properties of the prepared biomaterials were characterized using FE-SEM, FT-IR analysis, and physical properties.
View Article and Find Full Text PDFThe aim of this study was to prepare niacinamide (NA) imprinted biomaterials for treating hyperpigmentation using mungbean starch (MS), PVA, and plasticizers (glycerol (GL) and citric acid (CA)). Biomaterials and NA were characterized by FE-SEM, FT-IR, and H NMR. To evaluate the applicability of the NA imprinted biomaterials for a transdermal drug delivery system (TDDS), NA release experiment was conducted in different pH and temperature conditions.
View Article and Find Full Text PDFIntroduction: Vaccination continues to be the most effective method for controlling COVID-19 infectious diseases. Nonetheless, SARS-CoV-2 variants continue to evolve and emerge, resulting in significant public concerns worldwide, even after more than 2 years since the COVID-19 pandemic. It is important to better understand how different COVID-19 vaccine platforms work, why SARS-CoV-2 variants continue to emerge, and what options for improving COVID-19 vaccines can be considered to fight against SARS-CoV-2 variants and future pandemics.
View Article and Find Full Text PDFThe main objective of this study was to prepare functional allopurinol (ALP) incorporated biomaterials using mungbean starch, polyvinyl alcohol, melanin (MEL), and plasticizers. Prepared biomaterials were characterized by FE-SEM and FT-IR analysis. Photothermal conversion efficiencies and ALP release properties of biomaterials were evaluated with NIR laser irradiation.
View Article and Find Full Text PDFIn this study, we prepared chitosan beads cross-linked with epichlorohydrin (CB-ECH) to improve the removal of nitrate in groundwater. It was confirmed that CB-ECH exhibited higher thermal stability and well-developed nano-pores compared to the pure chitosan beads (CB) by the thermogravimetric analyzer, nitrogen gas adsorption and desorption isotherm, and field emission scanning microscopy analysis. The CB-ECH showed a higher nitrate adsorption amount than the pure CB.
View Article and Find Full Text PDFThis study focuses on the synthesis of functional allopurinol (ALP) imprinted biomaterials for a transdermal drug delivery using mung bean starch (MBS), polyvinyl alcohol (PVA), sodium benzoate (SB) as a crosslinking agent, and poloxamer (PX) as a thermo-sensitive polymer. Prepared functional biomaterials were characterized and evaluated by SEM, FT-IR analysis, and physical properties. Results of ALP recognition properties indicated that adsorbed amounts (Q) of ALP on functional ALP imprinted biomaterials were 3.
View Article and Find Full Text PDFThe main objective of this work was to prepare inulin (INL)/polyvinyl alcohol (PVA) biomaterials imprinted with arbutin (AR) as the target drug. INL from Jerusalem artichoke flour was extracted with hot water extraction method. INL/PVA biomaterials were synthesized with a casting method and a UV curing.
View Article and Find Full Text PDFShiga toxin-producing (STEC) are critical foodborne pathogens, which cause serious human health issues, including hemolytic uremic syndrome. Illnesses caused by STEC lack effective treatments that target the elimination of these bacteria from the gastrointestinal tract without causing an adverse effect. Reducing this pathogen from a reservoir of STEC is an effective strategy, but the challenges remain due to the lack of efficient, selective antimicrobial agents.
View Article and Find Full Text PDFIn this study, walnut-shaped V₂O₃ particles with high photocatalytic activity in the visible light were synthesized by hydrothermal process. The V₂O₃ samples synthesized with the various temperature conditions of the hydrothermal process were characterized using XRD, SEM, TEM, UV-Visible spectrometer and N₂gas adsorption/desorption analysis. For investigating the photocatalytic performance of synthesized V₂O₃ particles in the visible light condition, photodegradation experiments of methylene blue (MB) solution under artificial sunlight irradiation was conducted.
View Article and Find Full Text PDFCarbohydr Polym
September 2019
In this study, biodegradable biomaterials were prepared by using inulin (INL), PVA and plasticizers (citric acid (CA), glycerol (GL) and thiamine (TH)) with UV curing process. INL was extracted from Jerusalem artichoke flour using hot water extraction method. Extracted INL and INL/PVA biomaterials were characterized by TLC, FT-IR, and SEM analysis.
View Article and Find Full Text PDFIn this work, biodegradable biomaterial films for sulindac (SLD) recognition are synthesized from mungbean starch (MBS), PVA, and plasticizers by using UV irradiation process and casting methods. The optimal UV irradiation time for the preparation of SLD imprinted biomaterials films was about 30 min. Mechanical properties, recognition ability, and SLD release property for prepared films were investigated.
View Article and Find Full Text PDFJ Nanosci Nanotechnol
April 2019
In this work, we prepared basalt based nanostructured zeolite 13X by alkali fusion and hydrothermal synthesis process. The sample prepared was characterized using XRD, SEM, and low-temperature nitrogen analysis. The adsorption equilibrium and kinetic characteristics of ammonia nitrogen (NH₄-N) and phosphate phosphorus (PO₄-P) were investigated.
View Article and Find Full Text PDFPhotothermal therapy requires a biocompatible material to absorb near-infrared (NIR) light and generate sufficient heat. Herein, we suggest natural melanin-loaded nanovesicles (melasicles) as photothermal therapeutic agents (PTA) for NIR mediated cancer therapy in vivo. The mean size of these melasicles was 140 ± 15 nm.
View Article and Find Full Text PDFJ Photochem Photobiol B
November 2017
Active blend films from chitosan-gallic acid (CGA) and polyvinyl alcohol (PVA) were prepared via a simple mixing and casting method through the addition of citric acid as a plasticizer. The CGA/PVA blend films were characterized using Fourier transform infrared spectroscopy (FT-IR). The mechanical properties including tensile strength (TS) and elongation at break (%E), degree of solubility (S) and swelling behavior (DS), water vapor adsorption, and antimicrobial activities of the CGA/PVA blend films with and without LED (light emitting diode)-UV irradiation were also investigated.
View Article and Find Full Text PDFThis paper reports on a method of preparing chitosan-based films to which sulfosuccinic acid (SSA) is added for crosslinking agent with/without UV curing treatment and applications of a coating materials for foods. The physical, thermal, and optical properties of the UV cured chitosan-based films are investigated including their tensile strength (TS), elongation at break (%E), degree of swelling (DS), solubility (S), and water vapor absorption as well as their biodegradability in soil and applicability of the coating on a fruit. We also evaluated the physical properties of the prepared films to which glycerol (GL), xylitol (XL), and sorbitol (SO) are added to be used as plasticizers.
View Article and Find Full Text PDFInt J Biol Macromol
November 2017
In this study, nanocomposite films were synthesized by chitosan (CH), PVA, ZnS, sulfosuccinic acid, and plasticizers. The nanocomposite films were cross-linked by the heat curing process. ZnS was synthesized by the reaction of Zn(CHCOO) and NaS2O·5HO in aqueous solution via a template-free hydrothermal process.
View Article and Find Full Text PDFInt J Biol Macromol
October 2017
The photothermal effect is used in a new drug release system to control drug delivery in a specific region. Melanin absorbs near-infrared (NIR) light with a high photothermal conversion efficiency, and as a result, an NIR laser can be used to induced drug release from alginate microparticles containing melanin (ALG-Mel microparticles). The temperature of the ALG-Mel microparticle solution at a concentration of 5mg/mL increased to 38.
View Article and Find Full Text PDFIn this work, ZnS microspheres consisting of nanoblocks were synthesized by a simple, template-free approach employing a hydrothermal reaction at different temperatures, using Zn(CH3COO)2 and Na2S2O3 · 5H2O as starting materials in the aqueous solution. The synthesized samples were characterized using field-emission scanning electron microscopy (FE-SEM), X-ray diffraction (XRD), and Brunauer-Emmett-Teller (BET). The photocatalysts were evaluated using photodecomposition of methylene blue under UV-C light.
View Article and Find Full Text PDFJ Nanosci Nanotechnol
August 2015
The preparation of a poly(vinyl alcohol)/poly(acrylic acid)/glyoxal film (PVA = poly(vinyl alcohol); PAA = poly(acrylic acid)) with high tensile strength and hydrophobic properties by using the crosslinking reaction for OH group removal is reported herein. PAA was selected as a crosslinking agent because the functional carboxyl group in each monomer unit facilitates reaction with PVA. The OH groups on unreacted PVA were removed by the addition of glyoxal to the PVA/PAA solution.
View Article and Find Full Text PDFJ Agric Food Chem
February 2014
The main objects of this study were to prepare the cross-linked potato starch/polyvinyl alcohol blend films with ascorbic acid (AsA) added as a plasticizer with and without heat curing and to examine their mechanical properties, elongation at break, degree of swelling, solubility, water vapor absorption, thermal properties, optical properties, and biodegradability. The specific surface area, pore volume, and topography of the films with and without heat curing were also investigated via nitrogen adsorption and desorption isotherms and atomic force microscopy analysis. The results indicate that the cured films possess mechanical, thermal, and optical properties enhanced compared to those of noncured films.
View Article and Find Full Text PDFThe aim of this work is to prepare starch/PVA composite films added nano-sized poly(methyl methacrylate-co-acrylamide) (PMMA-co-AAm) particles and to investigate the mechanical properties, water barrier properties, and soil burial degradation for the films. Composite films were prepared by using corn starch, polyvinyl alcohol (PVA), nano-sized PMMA-co-AAm particles, and additives, i.e.
View Article and Find Full Text PDFIn this study, biodegradable films were prepared by using corn starch, PVA, nano-sized poly(acrylamide-co-methyl methacrylate) (PAAm-co-MMA), nano-sized TiO2(P-25)/PAAm-co-MMA composite, and additives which are harmless to the human body, that is, glycerol (GL) and citric acid (CA). Nano-sized PAAm-co-MMA was synthesized by the method of emulsion polymerization. Also, nano-sized TiO2/PAAm-co-MMA composites were synthesized by wet milling for 48 h.
View Article and Find Full Text PDF