Publications by authors named "Soohyun Lim"

Article Synopsis
  • Metabolic syndrome (MetS) is a genetic condition featuring multiple metabolic risk factors, and its genetic background has been explored through extensive genome-wide studies, but not completely understood.
  • Researchers conducted a large-scale study involving nearly 5 million individuals in Europe, uncovering 1,307 genetic loci linked to MetS, mainly in brain tissues, and identified 11 key genes significantly related to the syndrome.
  • The study also revealed that MetS is associated with a range of diseases beyond just heart-related issues, and polygenic risk scores showed promise in predicting MetS across different populations, aiding future research on its genetic structure.
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Background And Purpose: The wearing-off (WO) phenomenon is the most common motor complication in advanced Parkinson's disease (PD), but its identification remains challenging. The 9- and 19-item Wearing-off Questionnaires (WOQ-9 and WOQ-19) are self-assessment tools for motor and nonmotor symptoms that are widely used for WO screening. We produced Korean versions of the WOQ-19 and WOQ-9 (K-WOQ-19 and K-WOQ-9) and investigated their validity and reliability.

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  • A novel method for deoxyfluorination of various alcohols using a nontrigonal phosphorus triamide allows for the activation of alcohols without a base.
  • This process incorporates an organic soluble fluoride donor and a triarylborane fluoride shuttling catalyst to facilitate the reaction.
  • The study also shows that this method expands on current deoxyfluorination techniques, allowing for the creation of homochiral secondary and tertiary alkylfluorides through stereoinversion of the original alcohol.
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A 3-year phytotron study was conducted in Suwon (37.27°N, 126.99°E), Korea, to evaluate and model the effects of elevated temperature on rice-weed competition.

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species is one of the most problematic weed species due to its high competitiveness and increasing herbicide resistance. Florpyrauxifen-benzyl, a new auxin herbicide, was recently introduced for management; however, the potential risk for the development of herbicide resistance in species has not been well-investigated. Thus, this study was conducted to evaluate the baseline sensitivity of species to florpyrauxifen-benzyl to estimate the risk of future resistance development.

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Pollen-mediated gene flow of genetically modified crops to their wild relatives can facilitate the spread of transgenes into the ecosystem and alter the fitness of the consequential progeny. A two-year field study was conducted to quantify the gene flow from glufosinate-ammonium resistant (GR) soybean (Glycinemax) to its wild relative, wild soybean (G. soja), and assess the potential weed risk of hybrids resulting from the gene flow during their entire life cycle under field conditions in Korea, where wild soybean is the natural inhabitant.

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A synthetic cycle for aryl C-F substitution comprising oxidative addition, ligand metathesis, and reductive elimination at a -symmetric phosphorus triamide (, P{N[-NMe-CH]}) is reported. Reaction of with perfluoroarenes (Ar-F) results in C-F oxidative addition, yielding fluorophosphoranes ·[F][Ar]. The -fluoro substituent is exchanged for hydride by treatment with DIBAL-H, generating hydridophosphoranes ·[H][Ar].

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Article Synopsis
  • The study examines the environmental risks of gene flow from genetically modified (GM) crops, specifically glufosinate-ammonium-resistant Brassica napus, to its conventional relatives in smallholder farming systems in Korea.
  • Results showed that hybridization rates were low, with the highest frequency occurring at a distance of 2 meters and decreasing significantly with distance; gene flow to related species like B. juncea was minimal.
  • The findings suggest that while long-distance gene flow is unlikely, there is a potential risk of gene flow between closely adjacent fields in these farming systems.
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Article Synopsis
  • This study investigates gene flow from genetically modified (GM) herbicide-resistant Brassica napus to its wild relatives through wind and bee pollination, which raises ecological concerns in agricultural settings.* -
  • Results show that the maximum gene flow to male sterile (MS) B. napus and B. juncea decreased significantly with distance from HR B. napus, with positive percentages only within close proximity; for MS R. sativus, there was no observed gene flow.* -
  • The findings indicate that small donor plots favor insect pollination over wind, highlighting the need for better management of gene flow to mitigate environmental risks.*
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Objective: This study was done to evaluate whether perioperative propranolol (ß-blocker) in ovarian cancer patients undergoing debulking surgery reduced perioperative tumor growth induced by surgical stress.

Methods: This was a prospective randomized single institution analysis. The primary objective was to compare the changes in CA 125 level (changes between preoperation day 2 and postoperative day 7).

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The complete chloroplast (cp) genomes of two Miscanthus species, M. sinensis and M. sacchariflorus, were sequenced and investigated for genes, genome size variation, and polymorphisms.

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The aim of this study was to identify the hepatoprotective effects of reynosin, sesquiterpenes from the leaves of Laurus nobilis, against thioacetamide (TAA)-induced apoptosis in primary hepatocyte cultures and an in vivo mouse model. Rat hepatocytes were isolated and pretreated with 0.13, 0.

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Purpose: To evaluate the efficacy and safety of the tension-free placement of a monofilament polypropylene mesh for the repair of an anterior vaginal wall prolapse (AVWP).

Materials And Methods: Women aged ≥ 30 years with an AVWP stage of II or greater were included. Forty-nine women underwent trans-vaginal repair using a Gynemesh™ PS.

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