Botanical formulation HX110B ameliorates PPE-induced emphysema in mice via regulation of PPAR/RXR signaling pathway.

Chronic obstructive pulmonary disease (COPD), an inflammatory lung disease, causes approximately 3 million deaths each year; however, its pathological mechanisms are not fully understood. In this study, we examined whether HX110B, a mixture of Taraxacum officinale, Dioscorea batatas, and Schizonepeta tenuifolia extracts, could suppress porcine pancreatic elastase (PPE)-induced emphysema in mice and its mechanism of action. The therapeutic efficacy of HX110B was tested using a PPE-induced emphysema mouse model and human bronchial epithelial cell line BEAS-2B.

Microbial Production of Melanin Pigments from Caffeic Acid and L-tyrosine Using and FCS-ECH-Expressing .

In this study, synthetic allomelanin was prepared from wild-type and recombinant BL21(DE3) strains. could produce 125.25 ± 6.

Exploring the Subjective Frame of References in the Development of Gerotranscendence in Korean Older Adults: Q Methodology.

This study aims to explore how older people structure the subjectivity that accompanies the development of gerotranscendence in late adulthood within a specific sociocultural context. Q methodology, a common method for assessing subjectivity, was applied. The four subjective frames of reference that accompany the development of gerotranscendence, represented by four corresponding Q-factors, were (a) generation awareness, (b) awareness of aging, (c) awareness of the big picture of life, and (d) awareness of temporality.

Effects of dangguijakyaksan on lower-extremity blood circulation disturbances in climacteric and postmenopausal women: Study protocol for a randomized, double-blind, placebo-controlled pilot trial.

Background: Climacteric women experience various disorders, including hot flush, depression, insomnia, arthralgia, and hand and foot numbness. Dangguijakyaksan is among the most common treatments for climacteric syndrome, and its effect on depression, insomnia, hot flush and quality of life (QOL) in climacteric women has been reported multiple times. A recent animal study found dangguijakyaksan decreased serum lipid factors and improved blood circulation in a menopausal rat model; however, these effects have not been assessed in clinical trials.

Dual effects of isoflavonoids from Pueraria lobata roots on estrogenic activity and anti-proliferation of MCF-7 human breast carcinoma cells.

Pueraria lobata root (PLR), well known as Kudzu root, has recently become commercially available in Western dietary supplements for menopausal symptoms. The scientific basis for its action has been attributed to the action of phytoestrogens. This study aimed to investigate the estrogen-like activity of isoflavonoids isolated from P.

The job analysis of Korean nurses as a strategy to improve the Korean Nursing Licensing Examination.

Purpose: This study aimed at characterizing Korean nurses' occupational responsibilities to apply the results for improvement of the Korean Nursing Licensing Examination.

Methods: First, the contents of nursing job were defined based on a focus group interview of 15 nurses. Developing a Curriculum (DACOM) method was used to examine those results and produce the questionnaire by 13 experts.

Relevance of the test content of the Korean Nursing Licensing Examination to nursing job.

Purpose: This study aimed at identifying if there is a relevance of content of the Korean Nursing Licensing Examination (KNLE) revised in 2014 to nursing job. It will be able to provide the validity of revised content of the KNLE.

Methods: From October 13 to November 13, 2015, print version of 8 duties with 49-tasks, 155-job item questionnaires were distributed to 1,305 hospital nurses and 202 nursing faculties in Korea.

[Development of a scale to measure Korean ego-integrity in older adults].

Purpose: Ego-integrity in older adults is the central concept related to quality of life in later life. Therefore, for effective interventions to enhance the quality of later life, a scale to measure ego-integrity in older adults is necessary. This study was carried out to develop a scale to measure ego-integrity in older adults.

Exploring ego-integrity in old adults: a Q-methodology study.

Background: Achieving ego-integrity involves fully accepting oneself and is important in quality of later life, but the concept of ego-integrity in old adults has not yet been well articulated in nursing practice.

Objectives: This study aimed to elucidate the concept of ego-integrity in late adulthood in terms of the range of meanings this concept embraces within contemporary Korean society.

Design: Q-methodology was applied, which represents a method for measuring subjectivity.

[The concept analysis of ego-integrity in the elderly].

Purpose: Ego-integrity in Erikson's stage theory is used frequently among health team members related to the care of the elderly and has specific meanings within the context of quality of life in later life. However, the concept of ego-integrity in the elderly has not been well articulated in the literature. This study was conducted clarify and conceptualize the phenomena of ego-integrity in the elderly.

[The effects on health information education for the deaf].

Purpose: The purpose of this study was to evaluate the effects on health information education for the deaf.

Method: One group pre-test and post-test research design was applied to 46 deaf people. The instrument developed by research team was used for data collection.