Genomic analysis of pancreatic cancer reveals 3 molecular subtypes with different clinical outcomes.

Pancreatic cancer has a very high mortality with a 5-year survival of <5%. The purpose of this study was to classify specific molecular subtypes associated with prognosis of pancreatic cancer using The Cancer Genome Atlas (TCGA) multiplatform genomic data.Multiplatform genomic data (N = 178), including gene expression, copy number alteration, and somatic mutation data, were obtained from cancer browser (https://genome-cancer.

A 5-Year Review of Acanthamoeba Keratitis Related to Wearing Contact Lenses in Korea.

Purpose: To investigate the presentation, clinical characteristics, and outcomes of Acanthamoeba keratitis (AK) in Busan, South Korea, over a 5-year period.

Methods: This retrospective study involved a review of the medical records of 16 patients (19 eyes in total) who were diagnosed with AK, related to wearing contact lenses, at the tertiary hospital, Pusan National University Hospital at Busan City, from December 2013 to December 2018.

Results: Nineteen eyes of 16 patients with a diagnosis of AK were identified.