Publications by authors named "Sonya Maher"
Transplantation
August 2021
Article Synopsis
- Human cytomegalovirus (CMV) infection can cause kidney transplant issues, especially when paired with acute rejection, and this study looks at CMV-induced antibodies in that context.
- Researchers used mice to assess immunoglobulin G (IgG) and complement deposition in various types of CMV-infected kidney transplants, comparing B cell-deficient recipients and the effects of treatment with immune sera.
- Findings showed that kidney transplants with certain CMV profiles had higher IgG and complement deposition, leading to more significant tissue damage, suggesting that the body's immune response to CMV plays a role in kidney transplant rejection.
