Growth of the corpus callosum in adolescents born preterm.

Objective: To examine the growth of the corpus callosum between adolescence and early adulthood in individuals who were born before 33 weeks' gestation (very preterm [VPT]) and its relation to neuropsychological function.

Design: A longitudinal cohort study of VPT individuals born between January 4, 1982, and December 29, 1984, and a term-born comparison group.

Setting: A long-term follow-up study into perinatal predictors of outcome after preterm birth at University College Hospital, London.

Altered functional neuroanatomy of response inhibition in adolescent males who were born very preterm.

Event-related functional magnetic resonance imaging (fMRI) was used to investigate the hypothesis that males who were born very preterm may show differences in relative strength of blood oxygen level dependent (BOLD) signals in selective brain areas during performance of a simple response inhibition task compared with term-born controls. Participants were eight males (mean gestational age at birth 28wks, [SD 2]; mean age at testing 16y, [SD 1] and 14 controls matched for sex, age (mean age 17y, [SD 1]), and IQ. A 'go-no-go' task was used to assess response selection and motor response inhibition in response to a visual stimulus.