Publications by authors named "Sony Suharsono"

Unlabelled: Drought tolerance in rice is controlled by several genes and is inherited quantitatively. Low genetic map density and the use of phenotypic traits that do not reflect the corresponding tolerance level have been obstacles in genetic analyses performed to identify genes that control drought-tolerant traits in rice. The current study aimed to construct a genetic map from high-density single-nucleotide polymorphism (SNP) markers generated from genome sequences of recombinant inbred lines (RILs), derived from IR64 × Hawara Bunar.

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Article Synopsis
  • Lung cancer patients with EGFR gene mutations receive treatment using tyrosine kinase inhibitors (TKIs), and the study aimed to assess methods for detecting these mutations in cell-free DNA before and after treatment.
  • Using various techniques (PCR-HRM, RFLP, and direct sequencing), researchers analyzed samples from 116 treatment-naïve patients and found that while 100% of cfDNA samples showed EGFR genotypes, the sensitivity of plasma testing for mutations was relatively low compared to cytological samples.
  • After three months of TKI treatment, new resistance mutations were detected in some patients' plasma, suggesting that these tests can identify treatment resistance early on despite low sensitivity in detecting certain mutations.
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Environmental pollution by potentially toxic elements (PTEs) has become a serious problem with increasing industrialization and the disturbance of natural biogeochemical cycles. Jatropha is an oilseed-bearing shrub with high potential for biodiesel production in arid regions. In this study, we examined the physiological responses of this plant to five representative PTEs (Cd, Cr, Cu, Ni, and Zn) in a hydroponic culture.

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Ethylene response factor 1 (ERF1) is an essential integrator of the jasmonate and ethylene signalling pathways coordinating a large number of genes involved in plant defences. Its orthologue in Hevea brasiliensis, HbERF-IXc5, has been assumed to play a major role in laticifer metabolism and tolerance to harvesting stress for better latex production. This study sets out to establish and characterize rubber transgenic lines overexpressing HbERF-IXc5.

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