Interactions Between Toxic Metals and Serum Micronutrient Level in Auto-mechanics in Ibadan Metropolis, Nigeria: a Pilot study.

Auto-mechanics who often work without safety measures are vulnerable to the harmful effects of toxic metals like lead (Pb) and cadmium (Cd). These toxic metals exert their deleterious effect by interacting with the micronutrients at their primary site of action. This study aimed to investigate the effects of toxic metal exposure on serum micronutrient levels of auto-mechanics in Nigeria.

Assessment of Renal Function Status in Steady-State Sickle Cell Anaemic Children Using Urine Human Neutrophil Gelatinase-Associated Lipocalin and Albumin:Creatinine Ratio.

Introduction: Sickle cell anaemia is characterized by defective haemoglobin synthesis and is associated with both endocrine and metabolic alterations. The effects of this clinical condition on kidney function are multifactorial and often begin early in childhood. This study aims to assess renal function in children with sickle cell anaemia using urine albumin:creatinine ratio (ACR) and urine human neutrophil gelatinase-associated lipocalin (NGAL).

Hypovitaminosis D Is Associated with Some Metabolic Indices in Gestational Diabetes Mellitus.

Background: Gestational diabetes mellitus (GDM), a pregnancy complication, is defined as any degree of glucose intolerance with onset or first recognition during pregnancy. Vitamin D deficiency and insufficiency has recently been recognized as a contributing factor to the pathogenesis of GDM, and this link might be associated with hyperglycemia, insulin resistance, and inflammation, which are implicated in GDM.

Objectives: This study aims at investigating the relationship between vitamin D, fasting plasma glucose (FPG), insulin, zinc, ferritin, and high-sensitivity C-reactive protein (CRP) in GDM.

Aetiology of vitreous haemorrhage in Guinness Eye Centre, Lagos University Teaching Hospital over a two year period (June 2007-May 2009).

Background: The Vitreous Humour is the transparent biological gel which fills the posterior 5/6th of the eyeball. Extravasations of blood into this delicate tissue may cause visual loss.

Objective: The study was to determine the causes and pattern of vitreous haemorrhage in Guinness eye centre, Lagos University Teaching Hospital.

Vernal keratoconjunctivitis at Guinness Eye Centre, Luth (a five year study).

Introduction: Vernal keratoconjunctivitis (VKC) (Spring Catarrh) is a chronic, seasonally exacerbated bilateral external allergic ocular inflammation which causes a lot of ocular discomfort to children and young adults and, in severe or poorly managed cases, can even lead to blindness.

Objectives: To determine age/sex distribution, seasonal pattern, and frequency of clinical features.

Methodology: A review of medical records of patients who presented with VKC between January 2001 - December 2006.