How Much Do We Know about Oral Cancer?-An Online Survey.

Introduction: Oral cancer (OC) is a disease with a high mortality rate due to its late recognition. Since the oral cavity is easily accessible for visual inspection, enabling early diagnosis, the education of healthcare workers about preventive oral examinations is critical. This research aimed to assess the level of participants' OC knowledge, as well as to raise awareness about this diagnosis.

Healing of apical periodontitis in type II diabetes mellitus patients: A prospective study.

Objective: This study aimed to compare the healing of periapical bone between type II diabetes patients and healthy patients after root canal treatment.

Subjects And Methods: This study included 26 diabetic patients and the control group with healthy patients matching the diabetic group in age and sex. The study included only teeth with satisfactory coronal restoration.

Impact of Smoking on the Healing of Apical Periodontitis after Nonsurgical Endodontic Treatment.

Objectives:  The aim of this prospective study was to compare the healing of periapical bone between smokers and nonsmokers after root canal therapy. The effects of duration and intensity of smoking on the healing rate of apical periodontitis were analyzed.

Materials And Methods:  Fifty-five smokers were included in this study.

Association of the self-reported socioeconomic and health status with untreated dental caries and the oral hygiene level in adult patients.

Background: Dental caries is a multifactorial disease and its management requires a thorough analysis of its etiological factors.

Objectives: The present study used a multivariate approach to investigate the associations of socioeconomic and health-related determinants with untreated tooth decay and level of oral hygiene in adult individuals.

Material And Methods: A cross-sectional study involved 597 adult patients.

Absence of Oral Opportunistic Infections in Patients with Inflammatory Bowel Disease Receiving Anti-TNF-α and Anti-Integrin-αβ Therapy.

Biological therapy of inflammatory bowel disease (IBD) carries an increased risk for the development of opportunistic infections due to immunomodulation. The aim of this study was to determine the prevalence and types of oral infections in IBD patients treated with biological (anti-TNF-α and anti-integrin-α4β7) and conventional medication protocols. The study included 20 IBD patients receiving anti-TNF-α therapy, 20 IBD patients receiving anti-integrin-α4β7 therapy and 20 IBD patients without immunomodulatory therapy.

Is Coronal Restoration a Predictor of Posttreatment Apical Periodontitis?

Objectives:  To investigate the posttreatment apical periodontitis (AP) in endodontically treated teeth through a multivariate approach and to analyze the relative importance of quality and type of coronal restoration as predictors of periapical disease.

Materials And Methods:  The present study sample was drawn within 2-year period from the 1,072 consecutive patients older than 18 years, first time attending the Dental Clinic of the Clinical Hospital Center Rijeka, Croatia. A total of 1,350 endodontically treated teeth were included in the study.

Coronal Restoration as a Predictor of Periapical Disease in Non-Endodontically Treated Teeth.

Objectives: To compare the frequency of apical periodontitis (AP) in non-endodontically treated teeth restored with full coverage crowns, amalgam and resin composite fillings, and to disclose the association of type and quality of coronal restoration with periapical disease.

Material And Methods: The cross-sectional study involved 597 subjects who attended the Dental Clinic of the Clinical Hospital Centre, Rijeka, Croatia for the first time. Data were collected by means of a clinical and radiological survey.

Empathy amongst dental students: An institutional cross-sectional survey in Poland and Croatia.

Aim: To determine and compare levels of empathy and its dimensions in Polish and Croatian dental students.

Methods: Fourth- and fifth-year dental students (N = 193) at the University of Rijeka and University of Silesia completed questionnaires to determine levels of overall empathy and its dimensions: compassionate care (CC), perspective taking (PT) and ability to stand in someone else's shoes (ASSES). Total empathy and its dimensions were analysed depending on the country of origin, year of study and gender of the participants.

Socio-economic and health status as a predictor of apical periodontitis in adult patients in Croatia.

Objective: A few studies focused on determinants of apical periodontitis other than technical or biological factors. This research aimed to investigate to what extent socio-economic and health status can predict apical periodontitis in adult patients.

Subjects And Methods: The cross-sectional study included 599 adult patients.

Salivary Flow Rate, Oral Yeast Colonization and Dental Status in Institutionalized and Non-Institutionalized Elderly.

Elderly people, especially those institutionalized in long-term care facilities, are at risk of various oral diseases. The aim of the study was to determine the incidence of hyposalivation and colonization/oral fungal infection of oral cavity with yeasts, as well as dental status in institutionalized and non-institutionalized elderly. The study included 280 institutionalized and 61 non-institutionalized elderly people.

Cytotoxicity of Two Bioactive Root Canal Sealers.

Objective: The aim of this study was to investigate the cytotoxicity of two different bioactive root canal sealers: one based on mineral trioxide aggregate, MTA Fillapex (Angelus, Solucoes Odontologicas, Londrina, PR, Brazil), and the other based on bioceramics, Endosequence BC Sealer (Brasseler, Savannah, Georgia, USA), in culture of mouse L929 fibroblasts.

Materials And Methods: Mouse fibroblasts (L929), obtained from subcutaneous connective tissue of mouse line C3Hf, were cultivated in plastic culture flasks in an incubator at 37şC, with 5% CO2 and 90% humidity. Freshly mixed Endosequence BC Sealer and MTA Fillapex (0.

Influence of tobacco smoking on dental periapical condition in a sample of Croatian adults.

Background: Since current evidences support a negative influence of tobacco smoking on the periodontal bone, an increased prevalence or severity of periapical lesions would be expected among smokers. The aim of this study was to investigate the difference in the periapical status of endodontically treated and untreated teeth in current smokers and never-smokers.

Methods: The cross-sectional study included 259 subjects, 108 current smokers and 151 never-smokers, presenting as new patients at the Dental Clinic of the Clinical Hospital Centre Rijeka, Croatia.

Influence of air abrasion and sonic technique on microtensile bond strength of one-step self-etch adhesive on human dentin.

The purpose of this in vitro study was to evaluate the microtensile bond strength of one-step self-etch adhesive to human dentin surface modified with air abrasion and sonic technique and to assess the morphological characteristics of the pretreated dentin surface. The occlusal enamel was removed to obtain a flat dentin surface for thirty-six human molar teeth. The teeth were randomly divided into three experimental groups (n = 12 per group), according to the pretreatment of the dentin: (1) control group, (2) air abrasion group, and (3) sonic preparation group.

Association of obesity with periodontitis, tooth loss and oral hygiene in non-smoking adults.

Background: Periodontitis was found to be significantly related to obesity as well as the number of missing teeth and oral hygiene. However, the studies addressing these relationships often included smokers and diabetics, and none was performed in Eastern European patients. The aim of this cross-sectional study was to investigate associations between obesity and periodontitis, oral hygiene, and tooth loss in a sample of non-smoking Croatian subjects aged 31-75 years.

Microleakage along glass-fibre posts cemented with three different materials after cyclic loading: a pilot study.

The purpose of this in vitro study was to evaluate microleakage along glass-fibre posts cemented with three different cements after cyclic loading. After post-space preparation, fifty obturated root canals were randomly divided into three experimental groups and two control groups. In group 1, Glassix posts were cemented using Harvard cement, in group 2, Fuji PLUS cement was used and in group 3, Variolink II was used for post cementation.

Coronally advanced flap alone or with connective tissue graft in the treatment of single gingival recession defects: a long-term randomized clinical trial.

Background: Numerous surgical approaches for the treatment of single gingival recession (GR) defects are documented in the literature. The aim of this 5-year, split mouth-design, randomized clinical trial was to evaluate the effectiveness of coronally advanced flap (CAF) alone versus CAF with connective tissue graft (CAF+CTG) in the treatment of single Miller Class I and II GR defects.

Methods: Thirty-seven patients with 114 bilateral, single Miller Class I and II GR defects were treated with CAF on one side of the mouth and CAF+CTG on the other side.

Obesity and oral health--is there an association?

Obesity has been associated with several chronic diseases, such as coronary heart disease, stroke, adverse pregnancy outcomes, diabetes, and mortality; however it has not been until recently that an increased body mass index (BMI) was also related to dental health, especially periodontitis. We conducted a research to determine whether oral health was related to BMI using a cross-sectional design. Of 320 non-smoking subjects aged 31-60 years recruited from the patients referred to Dental Clinic at the Clinical Hospital Center in Rijeka, Croatia, a detailed dental health status was completed for 292 subjects.

Implant prosthetic rehabilitation of the patients with mandibular resection following oral malignoma surgery.

Patient underwent mandibular resection due to surgical therapy of oropharingeal malignoma. Facial asymmetry and cosmetic distortion are frequent consequences of such interventions, which may also include deviation and intrusion of the mandible, motor and sensory disorders, abnormal intermaxillary relations and malocclusion. Implant-supported prosthesis could be an optimal solution to prosthodontic treatment of such patients.

Proinflammatory cytokine levels in saliva in patients with burning mouth syndrome before and after treatment with low-level laser therapy.

The aim of this study was to determine the levels of proinflammatory tumor necrosis factor-alpha (TNF-α) and interleukin-6 (IL-6) cytokines in whole unstimulated saliva in subjects with burning mouth syndrome (BMS) before and after treatment with low-level laser therapy (LLLT). BMS is characterized by a continuous, painful burning sensation in a clinically normal-appearing oral mucosa. A sample consisting of 40 consecutive subjects was selected on a voluntary basis from the pool of patients who presented for diagnosis and treatment of BMS at the Oral Medicine Unit of the Faculty of Medicine of the University of Rijeka.

Difference in the periapical status of endodontically treated teeth between the samples of Croatian and Austrian adult patients.

Aim. To compare the periapical status of endodontically treated teeth between Austrian and Croatian adult patients and determine its relation to age, sex, position of teeth, and length of root canal filling. Methods.

In vitro oxidative stress induced by conventional and self-ligating brackets.

Objective: To determine the in vitro oxidative stress induced by conventional and self-ligating brackets made of different materials.

Materials And Methods: The concentration of oxidative stress marker 8-hydroxy-2'-deoxyguanosine (8-OHdG) in DNA of murine fibroblast cells L929 after in vitro exposure to three types of conventional and four types of self-ligating brackets was assessed. To determine viability and changes in the number of cells before and after exposure, trypan blue dye was used.

Salivary levels of TNF-alpha and IL-6 in patients with denture stomatitis before and after laser phototherapy.

Objective: The aim of this study was to monitor therapeutic response by determining the level of proinflammatory cytokines TNF-alpha and IL-6 in whole unstimulated saliva in patients with denture stomatitis (DS), before and after laser phototherapy (LPT).

Background: DS is an inflammatory condition that occurs in subjects who wear dentures, and it is a common oral mucosal lesion. A potential noninvasive treatment for DS patients is LPT.

Vibrations produced during erbium:yttrium-aluminum-garnet laser irradiation.

The purpose of this study was to evaluate vibrations induced by an erbium:yttrium-aluminum-garnet (Er:YAG) laser in the non-contact mode and compare the vibrations with different pulse durations and energy parameters. The experiment was conducted on an extracted tooth built up in silicone impression material. The vibrations were measured by piezoelectric accelerometer for a super-short pulse (SSP), a very short pulse (VSP), and a short pulse (SP) at a frequency of 5 Hz for 1 s.

Tumor necrosis factor-alpha in peripical tissue exudates of teeth with apical periodontitis.

Aim: The aim of this study was to determine tumor necrosis factor-alpha (TNF-alpha) levels in periapical exudates and to evaluate their relationship with radiological findings.

Methodology: Periapical exudates were collected from root canals of 60 single-rooted teeth using absorbent paper points. TNF-alpha levels were determined by enzyme-linked immunosorbent assays.