Publications by authors named "Sonja L Kunz"
Objectives: The aim of this study was to investigate an integrated diagnostics approach for prediction of the source of aldosterone overproduction in primary hyperaldosteronism (PA).
Methods: 269 patients from the prospective German Conn Registry with PA were included in this study. After segmentation of adrenal glands in native CT images, radiomic features were calculated.
Article Synopsis
- The preferred treatment for patients with unilateral aldosterone-producing adenoma (APA) is adrenalectomy, though some may experience adrenal insufficiency (AI) post-surgery.* -
- Researchers studied 66 patients pre- and post-surgery, analyzing various data including hormone levels and clinical chemistry to identify factors associated with post-operative AI.* -
- Key findings indicated that low insulin levels during pre-operative glucose tests and poor suppression of glucocorticoids corresponded with higher risk of AI, though predictions based on these factors were inconsistent in validation tests.*