Publications by authors named "Sonja Katrin Schickhardt"

Article Synopsis
  • The study investigates the relationship between phosphate levels in aqueous humor and the risk of calcification in intraocular lenses (IOLs), especially in diabetic patients.
  • In vitro tests involved different IOL models exposed to varying phosphate concentrations to assess calcification using several analytical methods.
  • Results indicated that higher phosphate concentrations and longer exposure times significantly increased the risk of IOL calcification, supporting the hypothesis that diabetic conditions may elevate this risk.
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Opacification of intraocular lenses (IOLs) due to material changes is a serious complication that can compromise the good visual outcomes of uncomplicated cataract surgery. In hydrophobic acrylic IOLs, opacification can result from glistening formation, while in hydrophilic acrylic IOLs, there is a risk of calcification due to the formation of calcium phosphates within the polymer. Over time, various methods have been developed to investigate calcification in hydrophilic acrylic IOLs.

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Article Synopsis
  • Opacification from calcification in hydrophilic acrylic intraocular lenses is a significant complication after cataract surgery, leading to the need to remove the lens.* -
  • The study aimed to assess whether hydrophobic surface properties of some hydrophilic acrylic lenses could reduce the risk of calcification compared to standard hydrophilic and hydrophobic lenses.* -
  • Results showed that all hydrophilic lenses, regardless of their surface properties, experienced calcification, while the hydrophobic lenses did not, indicating that hydrophobic surfaces do not prevent crystal formation.*
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Opacification through calcification of hydrophilic acrylic intraocular lenses (IOL) is a severe complication after cataract surgery. Causing symptoms that range from glare through to severe vision loss, the only effective therapy is explantation of the opacified IOL so far. Although IOL calcification is a well-described phenomenon, its pathogenesis is not fully understood yet.

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