Comprehensive monitoring of a biphasic switchable solvent synthesis.

Biphasic reactions were investigated in a specially designed high pressure set-up that allows simultaneous fibre-optic ATR IR and ATR UV-Vis measurements in both phases. The scope of quantitative spectroscopic measurements is tested on the absorption of CO(2) in hexanol and a biphasic switchable solvent synthesis. For both systems, all substances including dissolved and gaseous CO(2) can be quantified and a constant total mass balance over all phases can be achieved for every component in the reaction system.