We examined a stroke patient (HWS) with a unilateral lesion of the right medial ventral visual stream, involving the right fusiform and parahippocampal gyri. In a number of object recognition tests with lateralized presentations of target stimuli, HWS showed significant symptoms of hemiagnosia with contralesional recognition deficits for everyday objects. We further explored the patient's capacities of visual expertise that were acquired before the current perceptual impairment became effective.
View Article and Find Full Text PDFElectrophysiological monkey and human neuroimaging studies have reported a lateralization of signal processing in object perception. However, it is unclear whether these results point to a unique topographically organized signal processing in either hemisphere, or if these results represent a rather negligible spatial organization of otherwise redundant object perception systems in both hemispheres. We tested a group of 10 patients with lesions to ventral object processing regions and spared primary visual functions with lateral presentations of different categories of object stimuli.
View Article and Find Full Text PDFThe two-visual-systems hypothesis (TVSH) postulates that memory-guided movements rely on intact functions of the ventral stream. Its particular importance for memory-guided actions was initially inferred from behavioral dissociations in the well-known patient DF. Despite of rather accurate reaching and grasping movements to visible targets, she demonstrated grossly impaired memory-guided grasping as much as impaired memory-guided reaching.
View Article and Find Full Text PDFBackground: Two thirds of stroke survivors experience motor impairment resulting in long-term disability. The anatomical substrate is often the disruption of cortico-subcortical pathways. It has been proposed that reestablishment of cortico-subcortical communication relates to functional recovery.
View Article and Find Full Text PDFJ Exp Psychol Learn Mem Cogn
May 2015
In this article, we propose and evaluate a new model framework of parallel componential multi-symbol number processing, generalizing the idea of parallel componential processing of multi-digit numbers to the case of negative numbers by considering the polarity signs similar to single digits. In a first step, we evaluated this account by defining and investigating a sign-decade compatibility effect for the comparison of positive and negative numbers, which extends the unit-decade compatibility effect in 2-digit number processing. Then, we evaluated whether the model is capable of accounting for previous findings in negative number processing.
View Article and Find Full Text PDFTranscranial magnetic stimulation (TMS) can be used to mask visual stimuli, disrupting visual task performance or preventing visual awareness. While TMS masking studies generally fix stimulation intensity, we hypothesized that varying the intensity of TMS pulses in a masking paradigm might inform several ongoing debates concerning TMS disruption of vision as measured subjectively versus objectively, and pre-stimulus (forward) versus post-stimulus (backward) TMS masking. We here show that both pre-stimulus TMS pulses and post-stimulus TMS pulses could strongly mask visual stimuli.
View Article and Find Full Text PDF