Publications by authors named "Sonika Achalli"

Article Synopsis
  • The study aimed to measure salivary copper levels in patients with oral submucous fibrosis (OSMF) compared to healthy individuals.
  • It involved 60 participants (30 OSMF patients and 30 healthy controls) with saliva samples analyzed for copper content, alongside clinical assessments and biopsies.
  • Results showed that OSMF patients had significantly higher salivary copper levels than controls across different age groups and that levels increased with the severity of OSMF stages.
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Dermatoglyphics is the study of various dermal configurations on the fingers, palms, and soles. These appear during the 12th week of intrauterine life and develop completely by the 24th week. It is said that they remain constant thereafter.

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To assess the relationship between dermatoglyphic patterns and various growth patterns of the mandible. Patients with Class I Skeletal relation were selected after clinical diagnosis followed by digitally tracing the cephalogram. The patients were subdivided into three groups of mandibular divergence patterns ie Average, Horizontal and Vertical.

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Introduction: Nasal septal deviation (NSD) and concha bullosa (CB) are associated with airway obstruction in mouth breathers. Mouth breathing is associated with alterations in maxillary growth and palatal architecture. The aim of our study was to determine the effect of the presence of CB and NSD on the dimensions of the hard palate using cone-beam computed tomography (CBCT).

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Background: Use of tobacco is often implicated in the development of oral diseases. Questionable accuracy of the traditional questionnaires to assess cigarette exposure necessitates the use of biomarkers like thiocyanate which provide a definitive quantitative measure.

Objective: To assess the rise in the level of thiocyanate for measurement of smoking behaviour in adults.

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Background: Carcinogenesis is a multistep process where a healthy cell has initially a precancerous stage and finally an early cancerous stage. The process of carcinogenesis can be divided into three stages of initiation, promotion, and progression. In this process, there is increased turnover, secretion, and/or shedding from malignant cells.

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Background: Type 2 Diabetes Mellitus is a very well known metabolic disorder that has reached epidemic proportions worldwide. Evidence suggests that oxidative stress increases in Diabetes Mellitus because of the excessive production of reactive oxygen species and an impaired antioxidant defence mechanism. This study estimated, compared and correlated the serum and salivary Superoxide dismutase levels in healthy subjects and subjects with Type 2 Diabetes Mellitus having oral manifestations.

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Background: Oral cancer is the third most common form of malignancies in India. In many cases it develops at the site of premalignant lesion. Transformation of normal tissue to premalignant lesion and further to oral cancer results in alteration in glycolytic pathway and hence the lactate dehydrogenase levels.

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