Publications by authors named "Sonia Terradas-Campanario"
Article Synopsis
- The study explores the benefits of nebulizing voriconazole for treating fungal lung diseases, highlighting its potential for better lung penetration and fewer side effects compared to traditional methods.
- Researchers conducted a retrospective analysis of ten patients, focusing on the preparation and delivery of a compounded voriconazole solution for nebulization.
- Results indicated that the nebulized solution was well tolerated, with no adverse effects or systemic absorption observed, but further research is required to evaluate its effectiveness.
Article Synopsis
- The study investigates the use of nebulized voriconazole for treating fungal lung diseases, noting its potential benefits like better lung penetration and fewer side effects compared to other delivery methods.
- It involved ten patients (nine adults and one child) who received compounded voriconazole solutions, showing no adverse effects and no drug absorption into the bloodstream.
- The findings suggest nebulized voriconazole could be a viable option, but more research is necessary to evaluate its effectiveness in treating these conditions.
Objective: To determine by experimentation whether micafungin and anidulafungin possess physicochemical properties suitable for nebulization.
Method: PH, osmolality, viscosity, density and chloride content were determined by pH monitoring, osmometry, viscometry, densitometry and potentiometry in two samples of different concentrations, 5 and 10 mg/mL each echinocandin. Results: The results obtained for micafungin solution were: pH 5.