Publications by authors named "Sonia Sofia"

: Out of 39.9 million adults living with HIV in 2022, 20 million were women. Despite bearing a significant burden, women remain underrepresented in clinical trials, including those for antiretroviral treatments (ART).

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Article Synopsis
  • Skin and soft tissue infections (SSTIs) are diverse conditions impacting skin and underlying tissues, with varied symptoms, severity, and causes.
  • A nationwide surveillance program in Italy aimed to gather extensive data on SSTIs, involving both inpatient and outpatient cases for a comprehensive analysis of clinical and microbiological aspects.
  • Over a three-year period, 478 adult patients were studied, focusing on infection types, pathogens, antimicrobial susceptibilities, co-morbidities, treatment duration, and length of hospital stay to enhance understanding of SSTI management in Italy.
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Skin and soft tissue infections (SSTIs) represent a wide range of clinical conditions characterized by a considerable variety of clinical presentations and severity. Their aetiology can also vary, with numerous possible causative pathogens. While other authors previously published analyses on several types of SSTI and on restricted types of patients, we conducted a large nationwide surveillance programme on behalf of the Italian Society of Infectious and Tropical Diseases to assess the clinical and microbiological characteristics of the whole SSTI spectrum, from mild to severe life-threatening infections, in both inpatients and outpatients.

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Adherence to antiretroviral therapy (ART) is a key issue for people with human immunodeficiency virus. Optimal adherence leads to benefits in terms of survival and quality of life, which do not occur with incomplete adherence. One factor that may influence adherence to ART is emotional unawareness deficits.

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Brucellosis is the most common zoonosis in the world and it is caused by ingestion of foods contaminated by Brucella spp. that is able to avoid the immune system and can involve every organ system. The bacteria may affect the Central Nervous System (CNS) directly or using phagocytic cells with the way of the "Trojan Horse Model".

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