Recent Advances in Biomolecular Patho-Mechanistic Pathways behind the Development and Progression of Diabetic Neuropathy.

Diabetic neuropathy (DN) is a neurodegenerative disorder that is primarily characterized by distal sensory loss, reduced mobility, and foot ulcers that may potentially lead to amputation. The multifaceted etiology of DN is linked to a range of inflammatory, vascular, metabolic, and other neurodegenerative factors. Chronic inflammation, endothelial dysfunction, and oxidative stress are the three basic biological changes that contribute to the development of DN.

Association between and Mutations and Progesterone Resistance in Endometriotic Epithelial Cell Line.

Although endometriosis is a benign disease, it is associated with cancer-related gene mutations, such as or . Endometriosis is associated with elevated levels of inflammatory factors that cause severe pain. In a previous study, we demonstrated that or mutations are associated with the activation of cell proliferation, migration, and invasion in a patient-derived immortalized endometriotic cell line, HMOsisEC10.

Annual gametogenic phenology of oyster, (Röding, 1798) collected from the west coast of Moheshkhali Island, Cox's Bazar, Bangladesh.

The current study aimed to describe the annual gametogenic phenology of the oyster (Röding, 1798) (=), which is found on the west coast of Moheshkhali Island, Cox's Bazar, Bangladesh. Samples were drawn monthly from the intertidal region during low tide, from which 20 adult individuals were selected at random for biometry and histology. The mean condition index (CI), a ratio of tissue wet weight (g) to shell length (cm), varied from 0.

Advancements in Genetic and Biochemical Insights: Unraveling the Etiopathogenesis of Neurodegeneration in Parkinson's Disease.

Parkinson's disease (PD) is the second most prevalent neurodegenerative movement disorder worldwide, which is primarily characterized by motor impairments. Even though multiple hypotheses have been proposed over the decades that explain the pathogenesis of PD, presently, there are no cures or promising preventive therapies for PD. This could be attributed to the intricate pathophysiology of PD and the poorly understood molecular mechanism.

Pediatric Hypertension: Parental Perception and Knowledge.

The prevalence of hypertension (HTN) among youngsters has increased recently. Often, it is underrecognized owing to a lack of routine blood pressure measurement in many health centers, partly due to the unavailability of instruments and possibly because of this perception that it is not the foremost problem in children. There is less information about the parental perception of childhood HTN from Bangladesh.

Multifunctional CoFe2O4/ZnO nanocomposites: Probing magnetic and photocatalytic properties.

Developing nanocomposites as efficient photocatalysts for eliminating hazardous contaminants is essential because of growing severity of water pollution. In this study, we have analysed the morphological, structural, magnetic, and optical properties of cobalt ferrite (CoFe2O4), and zinc oxide (ZnO) nanocomposites synthesized via hydrothermal approach and used for removal of rose bengal (RB) dye from contaminated water. X-ray diffraction (XRD) analysis of synthesized nanocomposite revealed two distinct phases that matched with CoFe2O4 and ZnO.

A Systematic Review of Quantitative and Qualitative Results of Randomized Controlled Trials Assessing the Effect of Yoga in Adult Women With Post-traumatic Stress Disorder: What Is Known So Far.

Yoga has been increasingly practiced in recent years, with many of its practitioners being female. Adults may seek a complementary and alternative medicine (CAM) modality, such as yoga, to attempt to alleviate symptoms related to mental health conditions such as post-traumatic stress disorder (PTSD). Our goal for this systematic review was to collect and analyze all available data from quantitative and qualitative reports of randomized controlled trials (RCTs) conducted over the past 10 years on the impact of yoga on women diagnosed with PTSD.

Adverse Side Effects of Crizotinib in the Treatment of Anaplastic Lymphoma Kinase-Mutated Non-small Cell Lung Cancer: A Systematic Review.

Lung cancer is the leading cause of cancer deaths worldwide, with the majority consisting of non-small cell lung cancer (NSCLC). Genetic mutations present an opportunity for targeted therapy, in addition to current mainstay treatments such as chemotherapy and radiotherapy. Overall, 5% of NSCLCs have an anaplastic lymphoma kinase (ALK) mutation, often prevalent in a younger population.

Effectiveness of Catheter Ablation in Left Ventricular Ejection Fraction, Stroke, Quality of Life, All-Cause Mortality, Sinus Rhythm Maintenance, and Hospitalization Rates as Compared to Medical Therapy.

Atrial fibrillation (AF) in the setting of heart failure (HF) accounts for a significant proportion of mortality. AF can be managed either with rate control or rhythm control strategies. Rate control involves the use of beta blockers or calcium channel blockers.

Parkinson's Neuropathology Puzzle: A Systematic Review Uncovering the Pathological Culprits Behind the Neurological Disease.

Being one of the most prevalent progressive neurodegenerative disorders (falling second only to Alzheimer's disease) with a clinical pattern affecting millions of lives all over the world, Parkinson's disease (PD) has never failed to attract a formidable interest from the vast majority of neurologists and researchers worldwide. This review article will analyze the pathophysiology, etiology, genetics, and pathological stages of Parkinson's disease with their corresponding clinical sequels. A review article was conducted using research databases including PubMed, PubMed Central, Springer, and Elsevier.

An Overview of Safety and Efficacy Between Hypoxia-Inducible Factor-Prolyl-Hydroxylase Inhibitors and Erythropoietin-Stimulating Agents in Treating Anemia in Chronic Kidney Disease Patients.

Anemia is one of the common complications in chronic kidney disease (CKD) patients. Erythropoietin and iron deficiencies are the major causes to develop anemia in CKD patients. Untreated anemia is associated with increased morbidity and mortality.

Contemporaneous and upcoming trends in immunotherapy for prostate cancer: review.

Prostate cancer (PCa) is the most common cancer in men worldwide. It affects more than 1.4 million men worldwide and kills up to 37 5000 people.

Meditation and Its Mental and Physical Health Benefits in 2023.

This article discusses the power of meditation and how beneficial it is for the body. Magnetic resonance imaging (MRI) has shown many positive brain changes and improved several brain functions. Meditation has several benefits improving the immune system and inflammatory processes by decreasing cytokine; appropriate telomere shortening also has helped healthy aging.

Carbapenem Resistance among Klebsiella pneumoniae in a Tertiary Care Hospital in Bangladesh.

Carbapenem-resistant K pneumoniae (CRKP) clinical isolates have spread widely now-a-days throughout the world. This study was designed to investigate the carbapenem resistance among Klebsiella pneumoniae and to see anitimicrobial susceptibility of these CRKP isolates to other antimicrobials in a tertiary care hospital in Bangladesh. K pneumoniae was detected by standard methods and various biochemical tests like Triple Sugar Iron (TSI) agar media, Simmons citrate agar media and Motility-Indole-Urea (MIU) agar media.

Floating raft culture of Gracilariopsis longissima for optimum biomass yield performance on the coast of Cox's Bazar, Bangladesh.

Seaweed cultivation is an eco-friendly method and attracts growing interest which needs a multi-criteria approach for its sustainability. In our present study, an economically significant red alga, Gracilariopsis longissima was cultured using a floating raft method on the coast of Cox's Bazar, Bangladesh for a period of 90 days from January to March 2022. The effects of different factors such as rope materials, culture type, raft shape, seeding intensity, harvesting phase and water depth on the biomass yield production of G.

Prevalence of Colistin Resistance in Klebsiella pneumoniae Isolated from a Tertiary Care Hospital in Bangladesh and Molecular Characterization of Colistin Resistance Genes among Them by Polymerase Chain Reaction and Sequencing.

Resistance to colistin, the last resort of treatment for multidrug resistant organisms has increased now-a-days. This cross-sectional study was conducted in the Department of Microbiology of Dhaka Medical College, Dhaka, Bangladesh, from July 2016 to June 2017 and was designed to investigate the colistin resistance profile along with the genetic background of colistin resistance among Klebsiella pneumoniae in a tertiary care hospital in Bangladesh. K.

Fibroblast growth factor receptor 1 protein (FGFR1) as potential prognostic and predictive marker in patients with luminal B breast cancers overexpressing human epidermal receptor 2 protein (HER2).

Context: Breast cancer is the most common cause of cancer mortality among women worldwide. It is a heterogeneous disease partly responsible for treatment failure in luminal B patients. Deregulation of fibroblast growth factor signaling has been found and its therapeutic/prognostic value is explored.

Renal Involvement in Children with Dengue Fever: A Study in Tertiary Care Hospital of Bangladesh.

: Dengue has emerged globally as the most relevant viral infection transmitted by a mosquito bite and represents a major threat to public health. Dengue-related renal manifestations such as proteinuria, hematuria, acute kidney injury (AKI), and rhabdomyolysis are not uncommon, and acute kidney injury (AKI) is a serious complication of dengue fever. There is relatively few data on the renal manifestations of dengue fever in children.

Diurnal variations of postural stability and attentional capacities in 5-6-year-old tennis players.

The present study aimed to investigate the diurnal variation of postural stability, attentional capacities, and oral temperature in 5-6-year-old tennis players. A total of 24 young children were divided into two groups: Twelve tennis players with 2 years of training experience and twelve sedentary children without previous experience in any type of sport. They were asked to maintain an upright bipedal stance on a static force platform with eyes open (EO) and eyes closed (EC) at 07:00, 10:00, 14:00, and 18:00 h.