Menopause and metabolic syndrome: anthropometric, lipid, and dietary profiles.

Objective: The aim of this study was to characterize the anthropometric, lipid, and dietary profiles of postmenopausal women with metabolic syndrome attending a public health service and compare them with a group of women without metabolic syndrome.

Methods: A cross-sectional study was conducted with 60 postmenopausal women who were divided into two groups: control group and metabolic syndrome group, attending the Climacteric Outpatient Clinic at Santa Casa de São Paulo Hospital, Brazil, between February 2019 and December 2021. Participants were evaluated using a validated semi-quantitative food frequency questionnaire, body mass index, waist circumference, and serum laboratory tests.

A randomized clinical trial of transdermal (gel) versus oral estrogen for endometrial preparation in frozen embryo transfer cycle.

Objective: The aim of this study was to compare endometrial thickness with the use of transdermal estrogen (gel) versus oral estrogen (pills) for endometrial preparation in the frozen embryo transfer cycle and serum estrogen concentrations during the preparation cycle, side effects, and chemical and clinical pregnancy rates.

Methods: This was a prospective, randomized controlled trial of women undergoing endometrial preparation for cryopreserved blastocyst transfer. A total of 88 women were randomized, of which 82 completed the study protocol.

Polycystic ovary syndrome and abdominal fat: is there a relationship?

Objective: The aim of this study was to compare the distribution of fat tissue in non-obese women with polycystic ovary syndrome and those without the syndrome using dual-energy radiological densitometry.

Methods: This was a case-control study in which we enrolled women aged 14-39 years with polycystic ovary syndrome according to the Rotterdam criteria with a body mass index between 18.5 and 30 kg/m2.

Cryopreservation as a strategy for prevention of ovarian hyperstimulation syndrome in a public assisted reproduction service in São Paulo - Brazil.

Objective: This study aimed to evaluate the prevalence of ovarian hyperstimulation syndrome (OHSS) and associated risk factors in patients undergoing fertilization cycles at risk of OHSS (≥15 antral follicles or ≥15 oocytes aspirated) and submitted to cryopreservation of all embryos in the Human Reproduction Service of the Pérola Byington Hospital (Referral Center for Women's Health) in São Paulo, SP, Brazil.

Methods: This cross-sectional, institutional, descriptive study of secondary data from patients' charts enrolled in the Assisted Reproduction Service of the Pérola Byington Hospital at risk of OHSS after controlled ovarian stimulation and submitted to cryopreservation of all embryos was conducted between January 2015 and September 2017.

Results: OHSS occurred in 47.

Effects of (L.) Nutt on sexual function in women receiving tamoxifen for breast cancer.

To assess the effects of (L.) Nutt on climacteric symptoms and sexual function in women receiving tamoxifen after breast cancer treatment. A prospective study of women treated at the Mastology Outpatient Clinic of the Department of Obstetrics and Gynecology of the Santa Casa de Sao Paulo School of Medical Science of the hospital was conducted between 2018 and 2021.

Oral dydrogesterone in frozen-thawed embryo transfer cycles.

Objective: The aim of this study was to compare the use of micronized vaginal progesterone and oral dydrogesterone in the endometrial preparation for frozen-thawed embryo transfer.

Methods: This was a randomized, controlled, open, two-armed clinical trial, with women undergoing frozen-thawed embryo transfer along with hormone replacement therapy for endometrial preparation, between September 2019 and February 2021. A total of 73 patients were randomly selected and orally administered 40 mg/day dydrogesterone (dydrogesterone group, n=36) or 800 mg/day micronized vaginal progesterone (micronized vaginal progesterone group, n=37), after endometrial preparation with transdermal estradiol.

Morbidities and medications used by practicing nurses during the climacteric.

Objective: This study aimed to identify the morbidities and medications used by nurses practicing in São Paulo, Brazil, during the climacteric period to raise awareness and contribute to future preventive health measures in this population.

Methods: A descriptive, cross-sectional study of 218 nurses aged 46-65 years based on data collected between January 2018 and July 2019 using a self-administered questionnaire was conducted.

Results: Respondents had a mean age of 53.

Garlic: An Alternative Treatment for Group B Streptococcus.

Prenatal screening in pregnant women between 35 and 37 weeks of gestation and intrapartum antibiotic prophylaxis has successfully reduced the incidence of neonatal morbidity and mortality related to Streptococcus agalactiae. However, the contamination rates of newborns are still considerable. In traditional and folk medicines, it has been observed that garlic has been effective in treating S.

Quality of Life and Climacteric Symptoms in Postmenopausal Women Receiving Hormone Therapy for Breast Cancer.

Objective: To assess quality of life and climacteric symptoms for post-menopausal women receiving hormone therapy for breast cancer.

Methods: A prospective observational study of women treated at the Mastology Outpatient Clinic of the Department of Obstetrics and Gynecology was conducted between 2015 and 2019. Post-menopausal patients who had been diagnosed with breast cancer and who were experiencing climacteric symptoms were selected.

Evaluation of Obesity Influence in the Sexual Function of Postmenopausal Women: A Cross-Sectional Study.

Objective:  The incidence of obesity, which is a chronic condition, has increased in recent years. The association between obesity and female sexual dysfunction remains unclear, particularly in postmenopausal women. In the present study, we evaluated whether obesity is a risk factor for sexual dysfunction in postmenopausal women.

Critical analysis of methods for assessing genitourinary syndrome of menopause used in clinical trials.

Objective: The aim of the study was to determine the most used methods for assessing genitourinary syndrome of menopause by the latest studies on the subject, and to critically assess their differences and comparability.

Methods: A narrative review of the literature was conducted, employing the terms genitourinary syndrome, vaginal atrophy, urogenital atrophy, and atrophic vaginitis, to analyze methods used to assess treatment efficacy. Only controlled randomized clinical trials assessing improvement of genitourinary syndrome of menopause, conducted in the last 5 years, and considering all types of treatment, were selected.

Assessment of the body composition of patients with polycystic ovary syndrome using dual-energy X-ray absorptiometry.

Objective: To compare the body composition among patients with polycystic ovary syndrome (PCOS) and patients without PCOS.

Methods: A cross-sectional study enrolled patients aged 12-39 years, with body mass index (BMI, calculated as weight in kilograms divided by the square of height in meters) at least 18.5 but below 25, who attended the Endocrine Gynecology Clinic of Santa Casa de Sao Paulo School of Medical Sciences, Brazil, between January 1, 2014, and July 31, 2015.

Activity of the aqueous extract of Schinus terebinthifolius Raddi on strains of the Candida genus.

 To evaluate the antifungal susceptibility profile of the aqueous extract of the bark of Raddi against the strains of the genus .  By using the disk diffusion method, 50 samples of the genus (; ; ; and ), isolated from patients receiving treatment at Hospital Santa Casa de Misericórdia de São Paulo, and 1 American Type Culture Collection (ATCC) sample of each species were tested against: the isolated aqueous extract of the bark of Raddi, isolated nystatin, and the association of nystatin and the aqueous extract of Raddi.  There were no significant differences regarding the different strains of tested.

Assessment of the Effects of Tribulus Terrestris on Sexual Function of Menopausal Women.

Objective: The aim of this study was to study the effects of Tribulus terrestris on sexual function in menopausal women.

Methods: This was a prospective, randomized, double-blind, placebo-controlled clinical trial that included 60 postmenopausal women with sexual dysfunction. The women were divided into two groups, placebo group and Tribulus group, and evaluated by using the Sexual Quotient-female version (SQ-F) and Female Intervention Efficacy Index (FIEI) questionnaires.

Effects of low dose of tibolone on steroid receptors and Bcl-2 on the postmenopausal endometrium.

Objective: A prospective randomized controlled trial was conducted to evaluate the effect of low dose of tibolone on the histology, expression of estrogen (ER) and progesterone receptors (PR) and Bcl-2 protein, in endometrium of postmenopausal women.

Method: Forty postmenopausal women consented to treatment and were allocated into two groups of 20 women: Group 1 (Control) without hormone replacement therapy (HRT); Group 2 (Tibolone) treatment at the dose of 1.25 mg/day of oral tibolone administered for a 24-week period.

Effects of Glycine max (L.) Merr. soy isoflavone vaginal gel on epithelium morphology and estrogen receptor expression in postmenopausal women: a 12-week, randomized, double-blind, placebo-controlled trial.

Objective: Evaluate the effects of vaginal administration of isoflavones derived from Glycine max (L.) Merr. as a treatment option for vaginal atrophy, on the morphology and expression of estrogen receptors in vaginal epithelium of postmenopausal women.

[Evaluation of sexual function in postmenopause women with metabolic syndrome].

Purpose: To evaluate sexual function in postmenopausal women diagnosed with metabolic syndrome.

Methods: Case-control study with 195 postmenopausal women (amenorrhea ≥1 year, FSH≥30 mIU/mL, aged 43 to 69 years) seen at the Department of Obstetrics and Gynecology, School of Medical Sciences of Santa Casa de São Paulo and in the Basic Units of the Family Health Program of São Paulo. Clinical data were collected, and body mass index and waist circumference were evaluated.

Effective treatment of vaginal atrophy with isoflavone vaginal gel.

Objective: To assess efficacy and tolerability of a isoflavone (Glycine max L. Merr.) vaginal gel to the treatment of vaginal atrophy in postmenopausal women.

Differential expression of estrogen and progesterone receptors in endometrial polyps and adjacent endometrium in postmenopausal women.

Objective: To evaluate the immunoexpression of estrogen receptor (ER) and progesterone receptor (PR) in gland and stromal cells of endometrial polyps in postmenopausal women.

Study Design: Thirty postmenopausal patients underwent operative hysteroscopies because of benign endometrial polyps. The polyps were identified and subsequently completely removed.

[Effects of tamoxifen on the expression of TGF-beta and p27 proteins in polyps and adjacent endometrium in postmenopausal women].

Purpose: to evaluate the effects of tamoxifen on the expression of TGF-beta and p27 proteins in polyps and adjacent endometrium of women after menopause.

Methods: prospective study with 30 post-menopausal women with diagnosis of breast cancer, taking tamoxifen (20 mg/day), presenting diagnosis of suspect endometrial polyps through transvaginal ultrasonography, and submitted to diagnostic and surgical hysterectomy to withdraw the polyps and adjacent endometrium. A immunohistochemical study has been done to verify the expression of the TGF-beta and p27 proteins in the polyps and adjacent endometrium.

Effects of Trifolium pratense and Cimicifuga racemosa on the endometrium of Wistar rats.

Objective: The aim of this study was to evaluate the effects of Trifolium pratense and Cimicifuga racemosa upon the endometrium of castrated female Wistar rats, comparing these results with a placebo and estradiol valerate.

Methods: Thirty-two adult castrated female Wistar rats were divided into four groups (eight rats per group) that receiving either tap water, estradiol valerate, isoflavones from T. pratense or deoxyactein from C.

Nerve fibers in uterosacral ligaments of women with deep infiltrating endometriosis.

Unlabelled: Endometriosis is a disease of high prevalence and enigmatic origin. One aspect not yet clarified is the relationship between endometriosis and nerve tissue.

Objective: To evaluate, by immunohistochemistry, the presence of sympathetic and parasympathetic nerve fibers in the uterosacral ligament and adjacent connective tissue in women with deep pelvic endometriosis and women without endometriosis.

Acute administration of 17beta-estradiol improves endothelium-dependent vasodilation in postmenopausal women.

Objectives: Estrogen's effect on endothelial function in postmenopausal women with mild hypertension but no other cardiovascular risk factors remains unclear. This study investigated the effect of an acutely administered therapeutic/low dose of 17beta-estradiol on vasodilation in this patient population.

Methods: Forearm blood flow (FBF) was measured in seven white, hypertensive (blood pressure 144 +/- 8/93 +/- 5 mmHg), postmenopausal (mean age: 54.