Publications by authors named "Sonia Lopez Letayf"
A pentapeptide AVIFM (CAP-p5) derived from the carboxy-terminus end of cementum attachment protein was examined for its role on proliferation, differentiation, and mineralization of human periodontal ligament cells (HPLC), and for its potential to induce cementum deposition in vivo. CAP-p5 capability to induce hydroxyapatite crystal formation on demineralized dentin blocks was characterized by scanning electron microscopy, μRAMAN, and high-resolution transmission electron microscopy. The results revealed that CAP-p5 promoted cell proliferation and cell differentiation and increases alkaline phosphatase activity of HPLC and mineralization at an optimal concentration of 10 μg/mL.
View Article and Find Full Text PDFThe objective of this study was to analyze the effectiveness of two intravitreal antiangiogenic drugs, ranibizumab and aflibercept, in a Mexican population over a period of 5 years, evaluating the improvement in visual acuity (VA) and central retinal thickness (CRT) in a real-world scenario. This is a retrospective study with subjects diagnosed with diabetic retinopathy (DR), proliferative diabetic retinopathy (PDR), and diabetic macular edema (DME) receiving intravitreal injections of ranibizumab and/or aflibercept. In this study, we analyzed 588 eyes of 294 patients who received intravitreal antiangiogenic injections.
View Article and Find Full Text PDFDiabetic retinopathy (DR) is one of the main complications of diabetes, and the management of the main control parameters explains only an 11% reduction in the risk of progressing to DR, leaving 89% to be explained by other factors or correlations between the usual factors that are currently unknown. The objective of this systematic review and meta-analysis is to evaluate the similarities and differences between the possible risk factors for developing DR when comparing the world to Latin American populations. The search was performed first for Latin American (LA) populations and a second search for non-Latin American (Non-LA) populations.
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- * Researchers implanted these constructs into rat skull defects and compared their effectiveness with other control groups, finding that the hOMSC constructs led to 86% new bone formation after 120 days, significantly outperforming the other methods.
- * Results showed that the hOMSC-derived cells successfully transformed into functional bone cells, suggesting that these engineered constructs have great potential for treating bone injuries due to their high integration and immunomodulatory properties.