Publications by authors named "Sonia Hamdi"
Article Synopsis
- The prevalence of heart failure (HF) is increasing in Tunisia, largely due to an aging population and rising rates of coronary artery disease and hypertension, yet there's limited data on patient demographics and care quality.
- The study aims to create the National Tunisian Registry of Heart Failure (NATURE-HF) by analyzing and following 1700 patients over a year, with assessments at 1, 3, and 12 months.
- Results will include tracking cardiovascular and overall mortality, hospital readmissions, and various clinical evaluations and treatment outcomes to gain insights into the management of HF in Tunisia.
Article Synopsis
- * The study found a 1-year all-cause mortality rate of 22.8% for acute heart failure (AHF) patients and 10.6% for CHF patients, with various factors like age and diabetes influencing these rates.
- * Results indicated that AHF has a poor prognosis, while outcomes for CHF patients are improving, highlighting potential variations based on different healthcare systems and patient characteristics.
Introduction: Echocardiography is an important tool for diagnosis of cardiac abnormalities that can impact the management and outcome of the sick newborn in the intensive care unit. A preliminary echocardiogram performed by the neonatologist under the supervision of a paediatric cardiologist for interpretation and review is an alternate when there is not a cardiologist on site. The aim of this study was to evaluate frequency of use, neonatal characteristics, and indications of neonatologist-performed echocardiography in a Tertiary Neonatal Care Centre in Tunisia.
View Article and Find Full Text PDFBackground: Anemia on admission is a powerful predictor of major cardiovascular events in patients presenting for acute coronary syndromes. We sought to determine the prevalence and prognostic impact of anemia in patients presenting for ST-elevation myocardial infarction (STEMI).
Methods: We analyzed data from a Tunisian retrospective single center STEMI registry.
Objectives: Little is known about the risk profile and in-hospital prognosis of elderly patients presenting for ST-elevation myocardial infarction (STEMI) in Tunisia. We sought to determine in-hospital prognosis of elderly patients with STEMI in a Tunisian center.
Methods: The study was carried out on a retrospective registry enrolling 1403 patients presenting with STEMI in a Tunisian center between January 1998 and January 2013.
Peroxisome proliferator-activated receptor γ (PPARγ) is a ligand-activated transcription factor involved in the regulation of lipid metabolism, diabetes, obesity, atherogenesis and inflammation. PPARγ genetic variation has been associated with metabolic and cardiovascular diseases. The aim of this study was to explore, for the first time, the relationship between PPARγ C161T polymorphism and the risk of ischemic stroke (IS) among patients with type 2 diabetes mellitus (T2DM).
View Article and Find Full Text PDFPlatelet glycoprotein IIb/IIIa is a membrane receptor which plays a key role in coronary artery disease and thrombotic events. However, there is a considerable controversy regarding the clinical impact of glycoprotein IIIa platelet antigen 1 (PlA1)/platelet antigen 2 (PlA2) polymorphism as a risk factor for myocardial infarction. To evaluate the association between glycoprotein IIIa PlA1/PlA2 polymorphism and 1-year cardiovascular events occurrence in aspirin-treated patients with stable coronary artery disease.
View Article and Find Full Text PDFThe aim of this study was to assess the association between "aspirin non responsiveness" in patients with coronary artery diseases (CAD) and the risk of major adverse cardiovascular events (MACE). 204 patients with CAD receiving aspirin (250 mg/d) were included. Both Collagen/Epinephrine Closure Time (CEPI-CT) and urinary Thromboxane B2 (uTxB2) concentration was used to determine the patients aspirin responsiveness.
View Article and Find Full Text PDFBackground: Aspirin (ASA) failure to inhibit in vitro platelet function had been termed ASA resistance. The prevalence of this phenomenon as measured with different platelet function tests varies widely among studies.
Objectives: In this study, we propose to determine the prevalence of ASA non-responsiveness in stable coronary artery patients using three different tests.