Publications by authors named "Sonia Gelis"

Article Synopsis
  • Betalactam antibiotics are the most common triggers for hypersensitivity reactions, and Rapid Drug Desensitization (RDD) is a method that helps patients temporarily tolerate these drugs.
  • There is a lack of standardized RDD protocols, making it essential to assess their safety and management concerning various factors like drug stability and administration.
  • A review of nine RDD protocols in a hospital over three years showed a 92.9% success rate in desensitizing patients, including those with confirmed allergies, highlighting the effectiveness of these protocols.
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Cofactors may explain why in some cases food ingestion leads to anaphylaxis while in others elicits a milder reaction or tolerance. With cofactors, reactions become more severe and/or have a lower allergen threshold. Cofactors are present in up to 58% of food anaphylaxis (FAn).

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