The use of propensity score matching to assess the benefit of the endometrial receptivity analysis in frozen embryo transfers.

Objective: To study the impact of the endometrial receptivity analysis (ERA) on live birth rates in frozen embryo transfer (FET) cycles.

Design: Retrospective cohort study.

Setting: A single, large, university-affiliated infertility practice.

Does progesterone supplementation improve pregnancy rates in clomiphene citrate and intrauterine insemination treatment cycles?

Aim: To investigate the effect of empiric use of luteal phase progesterone supplementation to improve endometrial receptivity in women undergoing treatment with clomiphene citrate in combination with intrauterine insemination (CC-IUI).

Design: Retrospective cohort analysis.

Setting: University fertility center.

Role of nuclear progesterone receptor isoforms in uterine pathophysiology.

Background: Progesterone is a key hormonal regulator of the female reproductive system. It plays a major role to prepare the uterus for implantation and in the establishment and maintenance of pregnancy. Actions of progesterone on the uterine tissues (endometrium, myometrium and cervix) are mediated by the combined effects of two progesterone receptor (PR) isoforms, designated PR-A and PR-B.

Misperception of estrogen activity in patients treated with an estrogen receptor antagonist.

Measurement of estradiol is an important marker of ovarian function. At low levels, accurate measurement has been difficult because of unique characteristics of immunoassay kits. We present this case to emphasize the importance of accurate estimation of estrogen activity and estradiol levels to avoid unnecessary surgical intervention.

Accessory and cavitated uterine mass with functional endometrium in an adolescent: diagnosis and laparoscopic excision technique.

Study Objective: Accessory and cavitated uterine masses (ACUM) with functional endometrium can be treated successfully with laparoscopic excision. The objectives of this report are to illustrate the surgical technique used for the removal of this uterine wall mass and to discuss the patient's clinical course and outcomes.

Design: Surgical technique and description of 1 case.

Diagnosis and management of endometrial hyperplasia.

Endometrial hyperplasia (EH), with or without atypia, is a common gynecologic diagnosis and a known precursor of endometrial carcinoma, the most common gynecologic malignancy. During the reproductive years, the risk of EH is increased by conditions associated with intermittent or absent ovulation, in particular, polycystic ovary syndrome. After menopause when ovulation has ceased, EH is more common in women with conditions that increase levels of circulating estrogen such as obesity or estrogen replacement therapy.