Publications by authors named "Sonia Costantino"
: We sought to investigate whether the 2012 Briganti nomogram may represent a potential prognostic factor of prostate cancer (PCa) progression after surgical treatment beyond European Association of Urology (EAU) risk categories. : From January 2013 to December 2021, data on PCa patients treated with robot-assisted radical prostatectomy at a single tertiary referral center were extracted. The 2012 version of the Briganti nomogram assessing the risk of pelvic lymph node invasion was used.
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- Botulinum neurotoxin A (BoNT-A) is being increasingly used to treat neurogenic lower urinary tract dysfunctions and overactive bladder in children and adolescents, which is a growing area in urology.
- A systematic review analyzed various studies from databases like PubMed and Scopus to evaluate BoNT-A's effectiveness in improving urinary incontinence and urodynamic parameters in this age group.
- Results showed that among 1521 patients, there was a significant improvement in urinary incontinence scores by about 75% within 3-6 months after treatment, with no major adverse effects reported.
Article Synopsis
- A systematic review and meta-analysis examined intra- and postoperative outcomes for robot-assisted radical prostatectomy (RARP) comparing DaVinci (DV-RARP) and Hugo™RAS (H-RARP) platforms.
- The study included eight research articles with over 1,100 patients, revealing no significant differences in operative time, blood loss, or postoperative outcomes between the two surgical methods.
- The only notable difference was longer docking time for H-RARP, and a lower node yield compared to DV-RARP, indicating a need for further evaluation on the effectiveness and biases in the existing studies.
Purpose: To systematically compare the evidence about surgical outcomes, postoperative complications, and sequelae of Radical cystectomy with urinary diversion with or without stent placement.
Material And Methods: A literature search was performed through PubMed, Scopus®, and Web of Science up to December 2023 in accordance with the Preferred Reporting Items for Systematic Review and Meta-analysis (PRISMA) statement. The study protocol was registered in PROSPERO (CRD 42023492384), and the research question was formulated according to the PICOs model.
An enduring debate in research revolves around the association between elevated endogenous testosterone levels and prostate cancer. This systematic review is intended to assess the present understanding of the role of endogenous testosterone in the diagnosis and treatment of low- and intermediate-risk prostate cancer. Our search strategy was the following: (endogenous testosterone) AND (((low risk) OR (intermediate risk)) AND ((diagnosis) OR (treatment))) AND (prostate cancer); that was applied to PubMed, Web of Science, and Scopus databases to identify pertinent articles.
View Article and Find Full Text PDFBriganti's 2012 nomogram is an independent predictor of prostate cancer progression in EAU intermediate-risk class: results from 527 patients treated with robotic surgery.
Asian J Androl
November 2024
The study aimed to test if Briganti's 2012 nomogram could be associated with the risk of prostate cancer (PCa) progression in European Association of Urology (EAU) intermediate-risk patients treated with robotic surgery. From January 2013 to December 2021, 527 consecutive patients belonging to the EAU intermediate-risk class were selected. Briganti's 2012 nomogram, which predicts the risk of pelvic lymph node invasion (PLNI), was assessed as a continuous and dichotomous variable that categorized up to the median of 3.
View Article and Find Full Text PDFIntroduction: Active surveillance (AS) is a viable strategy for managing small renal masses (SRMs) in lieu of immediate surgery, but concerns persist regarding its impact on delayed partial nephrectomy (PN) outcomes. We aimed to compare perioperative and pathological outcomes of patients initially on AS for SRMs, later undergoing PN, against those undergoing immediate PN.
Materials And Methods: Data were extracted from a prospective institutional database (January 2018-September 2023) for patients with cT1a renal masses.
Chyluria, an abnormal lymphatic disorder, results in excessive abdominal lymph drainage into the urinary system, causing protein loss, nutritional deficiencies, and immune issues. Mainly linked to parasitic infections in developed countries, non-parasitic causes like trauma or tumors are rare. Typically appearing in adults with bilateral involvement, management options include conservative or surgical approaches.
View Article and Find Full Text PDFBackground: To investigate the potential prognostic impact of Briganti's 2012 nomogram in EAU intermediate-risk patients presenting with an unfavorable tumor grade and treated with robot-assisted radical prostatectomy, eventually associated with extended pelvic lymph node dissection.
Materials And Methods: From January 2013 to December 2021, the study included 179 EAU intermediate-risk patients presenting with an unfavorable tumor grade (ISUP 3), eventually associated with a PSA of 10-20 ng/ml and/or cT-2b. Briganti's 2012 nomogram was assessed as both a continuous and dichotomous variable, categorized according to the median (risk score ⩾7% vs <7%).
Article Synopsis
- The study evaluated the effects of using abdominal drains during robot-assisted partial nephrectomy (RAPN) in terms of complications, recovery time, and pain management, comparing patients with drains to those without.
- Data from 342 patients revealed that those with drains experienced longer surgery times, more blood loss, and greater pain relief needs, though drain use did not significantly predict major complications.
- The findings suggest that omitting drains may be safe and that individualized decisions should consider patient and procedure-specific factors.
Article Synopsis
- * Renal hemangiomas, particularly venous ones, are often asymptomatic and may be found accidentally during other medical evaluations, making preoperative diagnosis difficult.
- * The article features a video demonstrating robot-assisted surgery for a renal vein hemangioma, highlighting the specialized skills required for managing this uncommon condition.