Publications by authors named "Sonia Ayari"
Objectives: To prospectively assess, using polysomnography (PSG), the evolution in obstructive sleep apnea (OSA) in infants with Robin Sequence (RS) during their first year of life and to evaluate the role of PSG in OSA treatment.
Methods: Prospective and longitudinal study conducted in 2 tertiary hospitals (2018-2021). Data from 2 PSG (PSG1 0-3 months of life, PSG2 6-10 months of life) performed in RS infants in different sleep positions/conditions (without treatment: supine [SP]; with treatment: lateral [LP], prone [PP], respiratory support) were analyzed.
Study Objectives: Sleep laboratory polysomnography is the gold standard for obstructive sleep apnea (OSA) diagnosis in infants, but its access remains limited. Oximetry-capnography is another simple and widely used tool that can provide information on the presence of desaturations and alveolar hypoventilation. However, its reliability is debated.
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- Cystic lymphatic malformations are due to abnormal development of lymphatic structures during embryonic growth.
- A case study discusses a preterm baby born at 34 weeks with a large cystic lymphatic malformation in her neck, causing breathing issues.
- The baby was treated with sirolimus, an mTOR inhibitor, alongside sclerotherapy, showing that early treatment can be safe and effective for such conditions.
Article Synopsis
- Tracheobronchial endoscopy in toddlers under general anesthesia can lead to acute hypoxemia, which may affect patient outcomes, prompting the need for better monitoring during the procedure.
- A study analyzed 96 endoscopic procedures from 2015 to 2018, revealing that 58% of cases experienced at least one low oxygen saturation episode, with a median hypoxic burden of 25%.
- Factors such as initial admission to general hospitals and the use of topical lidocaine for airway anesthesia were linked to lower risks of high hypoxic burden, which in turn correlated with increased chances of requiring invasive ventilation post-procedure and extended hospital stays.
Objective: Preliminary assessment of the efficacy of propranolol on subglottic hemangioma in children on a nation-wide scale.
Methods: Multicentric, retrospective study of clinical files of 14 children; pre- and post-treatment endoscopies.
Results: Mean age at diagnosis was 2.
Objectives: We assessed the intermediate-term and long-term efficacy of intralesional injection of cidofovir used with surgical excision in juvenile-onset recurrent respiratory papillomatosis.
Methods: The protocol was revised during the study, from endoscopy at 4-week intervals with intralesional injection of cidofovir at 5 mg/mL, to a 2-week interval and a 7.5-mg/mL dosage.
Management of postcricoid and upper esophageal hemangioma.
Int J Pediatr Otorhinolaryngol
January 2007
To discuss management of postcricoid and upper esophageal hemangiomas in infants. Four children presenting with progressive feeding and/or respiratory disturbance underwent endoscopy including systematic esophagoscopy revealing the hemangioma of the postcricoid area and extending to the lumen of the upper esophagus. In the three children with severe disturbance, systemic steroids were insufficient and open surgical excision brought the hemangioma under control.
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- - A study investigated how effective intralesional cidofovir therapy combined with surgery is for treating laryngeal papillomatosis in adults over time.
- - Nineteen patients underwent a series of cidofovir injections, with 89% achieving complete remission after an average of about 4 procedures and maintaining that remission for an average of 24 months.
- - Results showed that higher cidofovir concentrations and shorter injection intervals resulted in fewer treatments needed to reach remission, highlighting the therapy's effectiveness for this condition.
Objective: To assess cidofovir plasma concentration after intralesional airway administration for recurrent respiratory papillomatosis.
Design: Prospective study.
Setting: Tertiary care teaching hospital.
Objective: To limit restenosis after surgical repair of choanal atresia.
Material And Methods: A total of 20 children (age range 3 days to 11 years) with choanal atresia underwent surgical repair using a microdebrider via an intranasal approach. Surgery was guided by CT.
Controlled risk of stenosis after surgical excision of laryngeal hemangioma.
Arch Otolaryngol Head Neck Surg
December 2003
Objective: To evaluate the risk of subglottic stenosis after surgical excision of congenital subglottic hemangioma.
Design: Retrospective analysis and case series.
Setting: Tertiary care teaching hospital.