Synopsis of recent research by authors named "Sonia A Silva"
Sonia A Silva’s research primarily focuses on the pharmacological effects of triptans, particularly sumatriptan, on human vascular tissues, demonstrating variations in receptor functionality across different blood vessel types.!
One of her key findings indicated that the human uterine artery exhibits tachyphylaxis (a rapid decrease in response) to sumatriptan-induced contractions, contrasting with stable responses observed in human cerebral blood vessels, such as the basilar and middle cerebral arteries.!
Her studies also involved characterizing the contractile responses of the human basilar artery to various agonists, elucidating the 5-HT receptor subtypes and their roles in mediating vascular contractility responses to triptans and serotonin (5-HT).!
