Passive Inclination Sensor Based on a Patch Antenna with a Reconfigurable Water Load.

In order to ensure the safety and preserve the value of historical buildings, inclination is an essential parameter during the continuous structural health monitoring process. However, the wire and price of a traditional sensor limit application. This paper proposes a low-cost inclination sensor based on a patch antenna with a reconfigurable water load.

LncRNA LUESCC promotes esophageal squamous cell carcinoma by targeting the miR-6785-5p/NRSN2 axis.

Esophageal squamous cell carcinoma (ESCC) is one of the most prevalent gastrointestinal malignancies with high mortality worldwide. Emerging evidence indicates that long noncoding RNAs (lncRNAs) are involved in human cancers, including ESCC. However, the detailed mechanisms of lncRNAs in the regulation of ESCC progression remain incompletely understood.

CircHIPK3 regulates fatty acid metabolism through miR-637/FASN axis to promote esophageal squamous cell carcinoma.

The oncogenic role of circRNA in cancers including esophageal cancer (EC) has been well studied. However, whether and how circRNAs are involved in cancer cell metabolic processes remains largely unknown. Here, we reported that circRNA, circHIPK3, is highly expressed in ESCC cell lines and tissues.

miR-1301-3p promotes invasion and migration and EMT progression in esophageal cancer by downregulating NBL1 expression.

Background: Esophageal cancer (ESCA) is one of the most aggressive and lethal human malignant cancers. MicroRNA-1301-3p (miR-1301-3p) plays vital roles in a majority of malignancies. The aim of this study was to investigate the role of miR-1301-3p/NBL1 axis on ESCA cell invasion, migration, epithelial-mesenchymal transition (EMT) process, as well as its association with prognosis of ESCA patients.

Design, Synthesis, and Biological Evaluation of Novel Hybrids Containing Dihydrochalcone as Tyrosinase Inhibitors to Treat Skin Hyperpigmentation.

Excessive melanin deposition may lead to a series of skin disorders. The production of melanin is carried out by melanocytes, in which the enzyme tyrosinase performs a key role. In this work, we identified a series of novel tyrosinase inhibitor hybrids with a dihydrochalcone skeleton and resorcinol structure, which can inhibit tyrosinase activity and reduce the melanin content in the skin.

Crack detection for concrete bridges with imaged based deep learning.

Within the framework of intelligent bridge detection, a number of crack detection methods based on image processing techniques have been implemented. In this study, a combined novel approach with deep learning of a single shot multibox detector (SSD) and the eight neighborhood algorithm is proposed and applied to bridge crack image identification to provide an automatic method for crack detection. First, a large number of concrete crack images collected from the site were segmented and preprocessed for the establishment of a crack image dataset.

Identification of new potent anticancer derivatives through simplifying the core structure and modification on their 14- hydroxyl group from oridonin.

The natural product oridonin has the potential to be a broad-spectrum antineoplastic agent. To develop oridonin analogues with high potency, a series of novel oridonin analogues were designed and synthesized by removing the multiple hydroxyl groups of parent compound. The representative analogues 14, 19, and 26 exhibited potent anticancer effects against K562, MDA-MB-231, SMMC-7721, and MCF-7 cells.

A Capacitively-Fed Inverted-F Antenna for Displacement Detection in Structural Health Monitoring.

This paper presents a capacitive displacement sensor based on a capacitively fed inverted-F antenna (CFIFA) for displacement detection. The sensor is composed of a grounded L-shape patch and a rectangular upper patch, forming a capacitor between them. The asymmetric dipole model is adopted to explain the frequency shift and current distribution of the proposed antenna sensor at its first-order resonance.

Knockdown of miR-183 Enhances the Cisplatin-Induced Apoptosis in Esophageal Cancer Through Increase of FOXO1 Expression.

Background: As an important member of platinum-based chemotherapeutic drugs, cisplatin is effective and is commonly used in the treatment of esophageal cancer. However, repeated use of cisplatin usually causes severe side-effects on patients. Novel approaches should be explored to increase the sensitivity of cancer cells to cisplatin.

Long-Range Displacement Meters Based on Chipped Circular Patch Antenna.

This paper presents a passive wireless long-range displacement sensor that is based on the circular patch antenna, and the detecting range of the sensor can be customized. The sensor consists of a chipped circular antenna with two opened rectangular windows, a substrate, and a ground plate with a sloping channel. No bonding between the antenna and the ground plate allows for the chipped antenna to slide along the sloping channel.

Numerical and Experimental Verification of a Multiple-Variable Spatiotemporal Regression Model for Grout Defect Identification in a Precast Structure.

Due to the increased service life, environmental corrosion, unreasonable construction, and other issues, local defects inevitably exist in civil structures, which affect the structural performance and can lead to structural failure. However, research on grout defect identification of precast reinforced concrete frame structures with rebars spliced by sleeves faces great challenges owing to the complexity of the problem. This study presents a multiple-variable spatiotemporal regression model algorithm to identify local defects based on structural vibration responses collected using a sensor network.

Expression and significance of c-kit and epithelial-mesenchymal transition (EMT) molecules in thymic epithelial tumors (TETs).

Background: To investigate the expression and significance of c-kit and epithelial-mesenchymal transition (EMT) molecules (E-cadherin, N-cadherin, Twist, Snail) in thymic epithelial tumors (TETs).

Methods: The tissue microarray technology and immunohistochemistry MaxVisionTM-use kit were used to detect the expression of c-kit and EMT molecular markers in 150 cases of paraffin sections of TET tissue and analysis the correlation between c-kit and EMT molecules and explore the malignancy and the relationship of clinicopathological parameters between c-kit, EMT molecules and TETs.

Results: The expression difference of c-kit and EMT molecular markers (E-cadherin, N-cadherin, Snail, Twist) in TETs subtypes was statistically significant (P<0.

hsa_circRNA_100873 upregulation is associated with increased lymphatic metastasis of esophageal squamous cell carcinoma.

Circular RNAs (circRNAs) are a type of endogenous non-coding RNA with multiple binding sites that specifically bind to microRNAs (miRNAs) and serve an important role in cellular regulatory networks. Patients exhibit varying levels of lymphatic metastasis in a clinical setting. The present study investigated the association between circRNAs and lymphatic metastasis in esophageal squamous cell carcinoma (ESCC).

A Passive Wireless Crack Sensor Based on Patch Antenna with Overlapping Sub-Patch.

Monolithic patch antennas for deformation measurements are designed to be stressed. To avoid the issues of incomplete strain transfer ratio and insufficient bonding strength of stressed antennas, this paper presents a passive wireless crack sensor based on an unstressed patch antenna. The rectangular radiation patch of the proposed sensor is partially covered by a radiation sub-patch, and the overlapped length between them will induce the resonate frequency shift representing the crack width.

A Displacement Sensor Based on a Normal Mode Helical Antenna.

This paper presents a passive displacement sensor based on a normal mode helical antenna. The sensor consists of an external helical antenna and an inserting dielectric rod. First, the perturbation theory is adopted to demonstrate that both the electric intensity and magnetic intensity have a noticeable gradient change within the in-and-out entrance of the helical antenna, which will cause the sensor to experience a resonant frequency shift.

In vivo biocompatibility and mechanical properties of porous zein scaffolds.

In our previous study, a three-dimensional zein porous scaffold with a compressive Young's modulus of up to 86.6+/-19.9 MPa and a compressive strength of up to 11.

A novel porous natural polymer scaffold for tissue engineering.

Unlabelled: A novel porous polymer scaffold fabricated by salt-leaching method for tissue engineering was developed and the mechanical properties and porosity were investigated in our study. Scanning electronic microscopy (SEM) was employed to observe the morphology and structure of porous scaffolds. Cytocompatility of the porous scaffolds were evaluated, using HL-7702 cells as model, in terms of cell attachment and cell viabilities from 3 to 72 hours determined by MTT method.

Mechanical properties and in vitro biocompatibility of porous zein scaffolds.

A porous scaffold utilizing hydrophobic protein zein was prepared by the salt-leaching method for tissue engineering. The scaffolds possessed a total porosity of 75.3-79.