The voltage-gated potassium channel Kv1.5, which mediates the cardiac ultra-rapid delayed-rectifier (I) current in human cells, has a crucial role in atrial fibrillation. Therefore, the design of selective Kv1.
View Article and Find Full Text PDFA novel turn-on fluorescent probe with barbituric acid as a unique recognition group has been rationally designed and synthesized using a facile method for detecting hydrazine. The 5-((7-(dimethylamino)-4,5-dihydronaphtho [1,2-b] thiophen-2-yl)methylene)pyrimidine-2,4,6 (1H,3H,5H)-trione (DPT) probe displays a large emission signal ratio variation (more than a 40-fold enhancement) in the presence of hydrazine under neutral conditions. Interestingly, a novel recognition mechanism based on a hydrazine-triggered addition-cyclisation-retro aldol was proposed and confirmed.
View Article and Find Full Text PDFPedestrian detection and human pose estimation are instructive for reconstructing a three-dimensional scenario and for robot navigation, particularly when large amounts of vision data are captured using various data-recording techniques. Using an unrestricted capture scheme, which produces occlusions or breezing, the information describing each part of a human body and the relationship between each part or even different pedestrians must be present in a still image. Using this framework, a multi-layered, spatial, virtual, human pose reconstruction framework is presented in this study to recover any deficient information in planar images.
View Article and Find Full Text PDF© LitMetric 2025. All rights reserved.