Niche differentiation shaped the evolution of rhizobacterial antibiotic resistance in paddy fields: Evidences from spatial-temporal and chemical-biological scaling.

The rhizosphere serves as both a hotspot and an entry point for the proliferation and transformation of antibiotic resistance genes (ARGs). However, the ecological mechanisms governing the evolution of ARGs in rhizosphere soils remain poorly understood. This study showed that ARGs associated with efflux pumps were found to be significantly enriched in the rice rhizosphere, compared to bulk soils, with a deterministic assembly process.

Deposited dead algae influence the microbial communities and functional potentials on the surface sediment in eutrophic shallow lakes.

Dead algae deposition will change the nutrient transformation on the sediment-water interface. However, the key factors that drive nutrient turnover, particularly the influence of sediment microbiota, remain poorly understood. As a result, this study conducted an 80-day simulated incubation to investigate the effect of different deposition of death algae on microbial communities and functional potentials in sediments.

Long-term effects of dead algal deposition on sediment surfaces: Behavior of endogenous phosphorus release in sediments.

Algae blooms are frequently triggered owing to the improvements in aquatic trophic levels. The aggregated algae from these blooms are eventually dead and accumulate on sediment surfaces, impacting the microenvironment and phosphorus cycling in aquatic systems. However, research on the effects of naturally dead algal deposition on endogenous P release from sediments is lacking.

Impact of elevated CO on microbial communities and functions in riparian sediments: Role of pollution levels in modulating effects.

The impact of elevated CO levels on microorganisms is a focal point in studying the environmental effects of global climate change. A growing number of studies have demonstrated the importance of the direct effects of elevated CO on microorganisms, which are confounded by indirect effects that are not easily identified. Riparian zones have become key factor in identifying the environmental effects of global climate change because of their special location.

Development of Nitric Oxide-Donating Netarsudil Derivatives as a Synergistic Therapy for Glaucoma with Reduced Ocular Irritation.

Based on the synergistic therapeutic effect of nitric oxide (NO) and Rho-associated protein kinase (ROCK) inhibitors on glaucoma, a series of NO-donating Netarsudil derivatives were designed, synthesized, and their activities in vitro and in vivo were evaluated. Among them, ()- released an appropriate amount of NO in aqueous humor in vitro and displayed potent ROCK inhibition. Topical administration of ()- significantly lowered intraocular pressure in an acute ocular hypertension rabbit model and protected retinal ganglion cells in a magnetic microbead occlusion mouse model.

Combining the Elicitor Up-Regulated Production of Unusual Linear Diterpene-Derived Variants for an In-Depth Assessment of the Application Value and Risk of the Medicinal and Edible Basidiomycete .

To better assess the practical value and avoid potential risks of the traditionally medicinal and edible basidiomycete , which may arise from undescribed metabolites, a combination of elicitors was introduced for the first time to discover products from cryptic and low-expressed gene clusters under laboratory cultivation. Treating NJFU21 with the combination of five elicitors led to the upregulated production of a class of unusual linear diterpene-derived variants, including eleven new ones (-), along with three known ones (-). The structures and stereochemistry were determined by 1D and 2D NMR, HRESIMS, ECD, OR and VCD calculations.

Newcomers building social capital by proactive networking: A signaling perspective.

Social networks can aid newcomers' learning and adjustment and facilitate their performance. However, knowledge about how newcomers build their social networks from the ground up is limited. Extending the socialization literature, we propose a model delineating newcomer proactive networking as the driver of advice ties with peer newcomers, which in turn influence newcomer reputation among higher status organizational insiders.

Unpacking the effects of socialization programs on newcomer retention: A meta-analytic review of field experiments.

Decades of research conducted using field experiments and quasi-experiments have enabled us to accumulate causal evidence on the effectiveness of onboarding and socialization programs (SPs) across various contexts including employment, higher education, and military services. However, the literature is devoid of an integrated conceptual framework and a quantitative review evaluating the effect of such SPs on reducing newcomer turnover and its boundary conditions. In this study, we draw from a configurational approach to categorize strategic components of SPs, propose bundles of these components based on extant theories in the socialization literature, and examine the moderating effects of these bundles on the retention benefits of SPs.

Spatial coupling coordination and interactive response between green finance and green total factor productivity: geographical analysis based on Chinese provinces, 2010-2020.

Based on the panel data of 30 provinces in China from 2010 to 2020, this study uses the coupling coordination degree model (CCDM), spatial autocorrelation analysis, and the panel vector autoregression (PVAR) model to quantitatively examine the dynamic coordination and interactive response of green finance (GF) and green total factor productivity (GTFP). The results show that the coupling coordination degree (CCD) between GF and GTFP during the study period shows an overall increasing trend and significant regional differentiation and remains at the medium level, indicating large room for improvement. The CCDs of provinces fluctuate between the low and high types.

Regional differences, dynamic evolution, and spatial-temporal convergence of green finance development level in China.

Green finance has great potential for supporting environmental improvement, combating climate change, and the economical and efficient use of resources. In this study, based on the panel data of 30 provinces in China from 2010 to 2020, we used the weighted TOPSIS model to measure the green finance development level (GFDL) in China and its three major regions. The Dagum's Gini coefficient, kernel density estimation, Markov chain, and the convergence model are used to analyze the regional differences, dynamic evolution, and spatial-temporal convergence of GFDL in China.

Preparation of chitosan-iron oxide modified sludge-based biochar for effective removal of tetracycline from water: performance and mechanism.

The release of antibiotics has attracted wide attention due to their abuse and discharge. How to remove these emerging contaminants is an urgent need to be solved. In the present study, sludge-based biochar combining chitosan and iron oxide was prepared via municipal sewage sludge.

Behavior change versus stability during the college-to-work transition: Life course and the "stickiness" of alcohol misuse at career entry.

To what extent and under what conditions do college graduates disengage from employment-incompatible behaviors during the college-to-work transition? Drawing from the life course perspective, we proposed a model highlighting considerable stability of employment-incompatible behaviors during initial months of organizational socialization. Our model predicted that maturing out of such behaviors, which is expected by employers and beneficial to career adjustment, would be more likely to occur given a conducive transition context. Using a large dataset tracking graduates from their last semester in college to up to approximately 1.

Surface modification significantly changed the effects of nano-polystyrene on sediment microbial communities and nitrogen metabolism.

Nanoplastics are ubiquitous in the natural environment, and their ecological risks have received considerable attention. Surface modification is common for nanoplastics and an essential factor affecting their toxicity. However, studies on the potential effects of nanoplastics and their surface-modified forms on functional communities in aquatic systems are still scarce.

Long-term effects of Ag NPs on denitrification in sediment: Importance of Ag NPs exposure ways in aquatic ecosystems.

The widespread use of silver nanoparticles (Ag NPs) inevitably leads to their increasing release into aquatic systems, with studies indicating that the mode of Ag NPs entry into water significantly affects their toxicity and ecological risks. However, there is a lack of research on the impact of different exposure ways of Ag NPs on functional bacteria in sediment. This study investigates the long-term influence of Ag NPs on denitrification process in sediments by comparing denitrifies responses to single (pulse injection of 10 mg/L) and repetitive (1 mg/L × 10 times) Ag NPs treatments over 60-day incubation.

Influence of the Maillard Reaction on Properties of Air-Assisted Electrospun Gelatin/Zein/Glucose Nanofibers.

To develop biodegradable, sustainable, and environment-friendly functional food-packaging materials, gelatin/zein/glucose nanofibers were fabricated through air-assisted electrospinning and then crosslinked by the Maillard reaction under mild conditions (60 °C and 50% relative humidity) in this study. Compared to traditional electrospinning, air-assisted electrospinning increased the yield of nanofibers by 10 times, and the average diameter from 263 nm to 664 nm, while the airflow facilitated uniform and smooth nanofiber formation. During the Maillard reaction in 0-5 days, the gelatin/zein/glucose showed no morphology change.

TLR7/8 agonist (R848) inhibit bovine X sperm motility via PI3K/GSK3α/β and PI3K/NFκB pathways.

Sex-control technology have great economic value and is one of the hot topics in livestock research. To produce more milk, dairy farmers prefer female offspring. X/Y sperm separation is an effective method for offspring sex control.

Can the carbon metabolic activity of biofilm be regulated by the hydrodynamic conditions in urban rivers?

Hydrodynamic regulation is widely used to improve the water quality of urban rivers. However, it is yet to explore substantially whether hydrodynamics could regulate the metabolic activity of biofilm in such aquatic systems. Herein, the pilot experiment of hydrodynamics in the rotation tanks was designed, including two experiment phases, namely constant flow and adjusting flow for 21 days and 14 days, respectively.

Polystyrene nanoplastics change the functional traits of biofilm communities in freshwater environment revealed by GeoChip 5.0.

There is an increasing concern regarding the potential effects of nanoplastics (NPs) on freshwater ecosystems. Considering the functional values of biofilms in freshwater, knowledge on whether and to what extent NPs can influence the ecosystem processes of biofilms were still limited. Herein, the freshwater biofilms cultured in lab were exposed to 100 nm polystyrene NPs (PS-NPs) of different dosages (1 and 10 mg/L) for 14 days.

Job search self-regulation during COVID-19: Linking search constraints, health concerns, and invulnerability to job search processes and outcomes.

The COVID-19 pandemic has caused tremendous job loss and made it difficult for unemployed individuals to search for new jobs. Specifically, the pandemic has created numerous job search obstacles, such as increased childcare and community responsibilities, that interfere with job seekers' ability to search for a job. Yet, the job search literature has scantily examined the implications of such job search constraints for job seekers even in normal times, and the limited studies that do exist have produced mostly null findings.

Distinct microbial metabolic activities of biofilms colonizing microplastics in three freshwater ecosystems.

Concerns are growing about the increasing amounts of microplastics (MPs) and their ecological impacts, especially the influences of "plastisphere" in the freshwater ecosystems. Although the microbial structure and composition of biofilms are investigated, knowledge of their microbial functions remains limited. Herein, we investigated the functional diversity of carbon metabolism in biofilms colonizing one inert (glass) and two MPs as polyvinyl chloride (PVC) and polyethylene terephthalate (PET) substrates incubated for 44 days in situ in the Niushoushan River, the Qinhuai River, and Donghu Lake.

Effectiveness of stereotype threat interventions: A meta-analytic review.

This meta-analytic review examined the effectiveness of stereotype threat interventions (STIs). Integrating the identity engagement model (Cohen, Purdie-Vaughns, & Garcia, 2012) with the process model of stereotype threat (Schmader, Johns, & Forbes, 2008), we categorized STIs into 3 types: belief-based, identity-based, and resilience-based STIs. Combining 251 effect sizes from 181 experiments, we found an overall effect size of d = 0.

Effects of silver nanoparticles on coupled nitrification-denitrification in suspended sediments.

The effects of varying concentrations of Ag NPs on coupled nitrification and denitrification (CND) in two suspended sediments (SPSs) sizes were investigated using isotopic tracer method. In general, 0.5 and 5 mg/L Ag NPs had less effect on CND, while 2 and 10 mg/L Ag NPs exhibited the improvement and inhibition effect, respectively.