Publications by authors named "SongYi Han"

This study reports dicarboxylate cellulose nanofibrils (DCNF) as a novel reducing and supporting agent for producing silver nanoparticles (AgNPs) with high efficiency (63.82 % reduction) and loading (6.88 %) using UV light.

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In this study, lignin nanoparticles (LN) and octadecylamine-modified LN (LN-ODA) were utilized as coating materials to enhance the hydrophobic, antioxidant, and ultraviolet radiation-shielding (UV-shielding) properties of a TEMPO-oxidized nanocellulose film (TOCNF). The water contact angle (WCA) of the TOCNF was approximately 53° and remained stable for 1 min, while the modified LN-ODA-coated TOCNF reached over 130° and maintained approximately 85° for an hour. Pure TOCNF exhibited low antioxidant properties (4.

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has been implicated in various gastrointestinal disorders, including functional dyspepsia. This study aimed to compare the anti- activity and gastroprotective effects of three typical herbal formulas used for gastrointestinal disorders in Korea: Shihosogan-tang (ST), Yijung-tang (YT), and Pyeongwi-san (PS). Firstly, we assessed the total phenolic and flavonoid contents, as well as the antioxidative capacity.

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Prohibitin (PHB) is an essential scaffold protein that modulates signaling pathways controlling cell survival, metabolism, inflammation, and bone formation. However, its specific role in periodontium development remains less understood. This study aims to elucidate the expression pattern and function of PHB in periodontium development and its involvement in alveolar bone formation.

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Article Synopsis
  • Ginseng (Panax ginseng) is recognized for its potential health benefits, specifically in enhancing body temperature and gut health, though the exact mechanisms remain poorly understood.
  • This study shows that periodic supplementation with ginseng extracts positively influences body temperature and reduces inflammation in certain metabolic organs of rats experiencing induced hypothermia, likely affecting gut hormone levels and microbiota composition.
  • In laboratory tests, ginseng extracts were found to influence gene regulation related to the body’s internal clock and inflammation, potentially through direct cellular action or by interacting with gut microbiota, with involvement of PI3K-AKT signaling pathways noted as a key factor.
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Tropane alkaloids (TA) are natural toxins found in certain plants, including cereals, of which atropine and scopolamine are the main species of concern due to their acute toxicity. This study aimed to determine the occurrence of TA in cereal foods and assess the potential health risks associated with their consumption in Korea. TA levels were analyzed in 80 raw and 71 processed cereal samples, which were distributed throughout Korea in 2021, using ultra-performance liquid chromatography-tandem mass spectrometry.

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Article Synopsis
  • This study explores the relationship between herbal medicine (specifically Yijung-tang, or YJT) and gut microbiota in regulating body temperature and inflammation in hypothyroid rats.* -
  • YJT demonstrated protective effects against hypothermia and systemic inflammation, unlike traditional drugs like L-thyroxine, by altering gut microbiota and impacting signaling pathways related to thermoregulation.* -
  • The findings suggest that YJT might promote the body's thermogenesis and modulate gut health, potentially leading to advancements in microbiota-focused treatments in medicine.*
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Rapid, efficient and green method of Pd nanoparticles (PdNPs) synthesis on TEMPO-oxidized cellulose nanofibril (TCNF) is demonstrated here. The nanohybrid (PdNPs/TCNF) exhibited peroxidase and oxidase-like activities evident by the oxidation of three chromogenic substrates. Enzyme kinetic studies using 3,3',5,5'-Tetramethylbenzidine (TMB) oxidation uncovered the excellent kinetic parameters (low K and high V) and good specific activities of 215 U/g and 107 U/g for peroxidase and oxidase-like activities, respectively.

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Ethnopharmacological Relevance: Paeoniae Radix Rubra (PRR), the root of Paeonia lactiflora Pall., is a traditional Chinese medicine which has the effects of regulating various inflammatory diseases, treating blood stasis, and enhancing blood circulation.

Aim Of The Study: This study examined whether Paeoniae Radix rubra extract (PRRE) and Paeoniflorin (PF) affect mucin production, gene expression including MUC5AC, and protein expression related to the ERK pathway induced by TNF-α from human airway epithelial cells.

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Purpose: The beneficial effects of a combination therapy using and galactooligosaccharide (GOS) for the treatment of atopic dermatitis (AD) have not been elucidated.

Methods: Gene expressions of interleukin (IL)-4 and IL-13 from peripheral blood mononuclear cells and fecal abundance of . from 12-month-old infants were evaluated.

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Chemotherapy has been widely used as a clinical treatment for cancer over the years. However, its effectiveness is limited because of resistance of cancer cells to programmed cell death (PCD) after treatment with anticancer drugs. To elucidate the resistance mechanism, we initially focused on cancer cell-specific mitophagy, an autophagic degradation of damaged mitochondria.

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Nanozyme-based dye degradation methods are promising for the remediation of water pollution. Though Pd nanoparticles (PdNPs) are known to act as nanozymes, their dye degradation capability has not been investigated. Low nanozyme activities, easy aggregation, difficulties in recovery and reuse are the major challenges in achieving this.

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The purpose of this study was to identify the factors associated with depressive symptoms in individuals who have experienced self-quarantine because of coronavirus disease exposure or infection using Lazarus and Folkman's stress, coping, and adaptation theory, and George's Social Antecedent Model of Depression. This was a cross-sectional study that used data from the 2020 Korean Community Health Survey. A complex sample design was used to analyze the data.

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Solid electrolytes are highly important materials for improving safety, energy density, and reversibility of electrochemical energy storage batteries. However, it is a challenge to modulate the coordination structure of conducting ions, which limits the improvement of ionic conductivity and hampers further development of practical solid electrolytes. Here, we present a skeleton-retained cationic exchange approach to produce a high-performance solid electrolyte of LiZrSiPO stemming from the NASICON-type superionic conductor of NaZrSiPO.

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This study reports the preparation of a polybutylene succinate (PBS) film reinforced with pure cellulose nanofibril (PCNF) and lignocellulose nanofibril (LCNF) by a two-step process that consists of solvent dispersion and twin-screw extrusion. Compared to the conventional one-step process, this method offered improved mechanical properties. The addition of 5% CNF increased the tensile properties up to 18.

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Article Synopsis
  • A cellulose acetate (CA)/cellulose nanofibril (CNF) film was created using a solvent casting method, where CNF serves as a reinforcement to enhance the film's tensile strength.
  • The study tested different ratios of CNF (3, 5, and 10 parts per hundred) and experimented with eco-friendly plasticizers (triacetin and triethyl citrate) along with two solvents (acetone and NMP).
  • Results indicated that using NMP for dispersion improved the film's mechanical properties significantly, with up to a 38% increase in tensile strength and a 65% increase in elastic modulus compared to pure CA, especially with a maximum effective CNF loading of 5 phr.
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Lignocellulose nanofibrils (LCNFs) with different lignin contents were prepared using choline chloride (ChCl)/lactic acid (LA), deep eutectic solvent (DES) pretreatment, and subsequent mechanical defibrillation. The LCNFs had a diameter of 15.3-18.

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In this study, the effect of lignin esterification with fatty acid chloride on the properties of lignin and lignin/poly(lactic acid) (PLA) composites was investigated. Lignocellulose ( S. et Z.

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  • Ginseng, particularly Korean red ginseng (KRG), has a long history in treating metabolic syndrome (MS), but how it works is not fully understood; recent studies suggest gut microbiota may play a key role.
  • A clinical trial involving 60 MS patients tested the effects of KRG over 8 weeks, measuring various health indicators and gut microbial composition, while categorizing subjects based on their responses to treatment and gut profiles.
  • The results showed that KRG significantly lowered systolic blood pressure and improved lipid metabolism in certain responders; specific gut microbial populations were associated with better treatment outcomes, indicating that these microbes could be useful biomarkers for personalized MS treatment.
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We aimed to improve the mechanical properties of alginate fibers by reinforcing with various cellulose nanofibrils (CNFs). Pure cellulose nanofibril (PCNF), lignocellulose nanofibril (LCNF) obtained via deep eutectic solvent (DES) pretreatment, and TEMPO-oxidized lignocellulose nanofibril (TOLCNF) were employed. Sodium alginate (AL) was mixed with PCNF, LCNF, and TOLCNF with a CNF content of 5-30%.

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Stethoscopes have been suggested to be a possible vector of contact transmission. However, only a few studies have focused on the prevalence of contamination by multidrug-resistant (MDR) bacteria and effectiveness of disinfection training to reduce. This study is to investigate the burden of stethoscope contamination with nosocomial pathogens and multidrug-resistant (MDR) bacteria and to analyze habit changes in disinfection of stethoscopes among healthcare workers (HCWs) before and after education and training.

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The molecular mechanisms that underlie the detrimental effects of particulate matter (PM) on skin barrier function are poorly understood. In this study, the effects of PM2.5 on filaggrin (FLG) and skin barrier function were investigated in vitro and in vivo.

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This study was conducted to identify the effects of social networks on unmet medical needs among older adults with limited instrumental activities of daily living (IADL) who live in a community. This study analyzed data from 2281 older adults with limited IADL from the 2017 National Survey of Older Koreans. Data were analyzed using descriptive statistics, X2 tests, -tests, and logistic regression analysis.

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Changes in the dimensions of lignocellulose nanofibrils (LCNFs) with different lignin contents from betung bamboo () by enzymatic hydrolysis using endoglucanase (EG) were investigated. Lignin contents were adjusted from 3% to 27% by NaClO/acetic acid treatment, and LCNFs were prepared using a wet disk-mill (WDM). The dimensions of the LCNFs significantly decreased with decreasing lignin content and increasing EG addition.

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A novel microwave-assisted green method that synchronously synthesizes silver nanoparticles (AgNPs) and AgNPs decorated holocellulose nanofibrils (AgNPs/HCNF) within a minute and without using a reducing agent is reported. As obtained nanomaterials were well characterized using various analytical techniques. AgNPs applied as a colorimetric probe for the selective recognition of Hg(II) (linear range 10-200 μg L, detection limit 1.

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