[Role of epithelial sodium channel in rat osteoclast differentiation and bone resorption].

Objective: To explore the role of epithelial sodium channel (ENaC) in regulating the functional activity of osteoclasts.

Methods: Multinucleated osteoclasts were obtained by inducing the differentiation of rat bone marrow cells with macrophage colony-stimulating factor (M-CSF) and RANKL. The osteoclasts were exposed to different concentrations of the ENaC inhibitor amiloride, and the expression of ENaC on osteoclasts was examined using immunofluorescence technique.

[The role of apoptosis in herpes simplex virus I type myocarditis of mouse].

Objective: To explore the relation among apoptosis of myocardial cell and the expression of TGF-beta1 in VMC.

Methods And Results: In the experiment, Viral myocarditis (VMC) in BALB/C mouse was obtained by inculating herpes simplex virus I type into abdominal cavity. The rate of VMC was 91.