Publications by authors named "Song-ping Yu"
Article Synopsis
- - This study examined how vitamin D levels might influence various eye disorders using genetic data from large research studies involving over 700,000 European individuals.
- - Results indicated a causal link between higher genetically predicted vitamin D levels and an increased risk of wet age-related macular degeneration (WAMD), while most other ocular disorders showed no significant association.
- - The findings suggest that vitamin D could play a role in WAMD, providing valuable insights for future research and potential interventions in eye health.
Aim: To evaluate the effects of LIN28A (human) on high glucose-induced retinal pigmented epithelium (RPE) cell injury and its possible mechanism.
Methods: Diabetic retinopathy model was generated following 48h of exposure to 30 mmol/L high glucose (HG) in ARPE-19 cells. Quantitative real-time polymerase chain reaction (qRT-PCR) and Western blot tested the expression of the corresponding genes and proteins.
Purpose: We conducted a systematic review and meta-analysis to investigate the efficacy and safety of single-dose intravitreal dexamethasone (DEX) implant for treating non-infectious uveitic macular edema (UME).
Methods: Studies including clinical outcomes of the DEX implant in UME were comprehensively searched in PubMed, Embase, and Cochrane databases for potential studies from inception to July 2022. The primary outcomes were best corrected visual acuity (BCVA) and central macular thickness (CMT) during the follow-up period.
[Effects of environment and canopy structure on stem sap flow in a plantation].
Ying Yong Sheng Tai Xue Bao
May 2021
Article Synopsis
- The study investigates how environmental factors like meteorological conditions, soil water content, and canopy structure affect tree sap flow in a specific area of the Liupan Mountains from June to September 2019.
- Researchers found that the sap flow rate is influenced by potential evapotranspiration (PET), relative extract water (REW), and canopy leaf area index (LAI) in varying degrees, leading to different response patterns for each factor.
- A model was developed to predict sap flow by considering the interactions among PET, REW, and LAI, revealing that PET is the most significant factor, particularly varying greatly between sunny, cloudy, and rainy days.
Aim: To investigate the effects of high glucose (HG) medium on expression of hypoxia-inducible factor-1α (HIF-1α) and vascular endothelial growth factor (VEGF) in cultured rat retinal Müller cells and to determine the signaling pathways mediating the effects.
Methods: Primary cultures of retinal Müller cells were prepared from Sprague-Dawley rats, and incubated in a medium containg HG (30 mmol/L) in the presence of the membrane-permeable Ca(2+) chelator BAPTA-AM (10 μmol/L) or the CaMKII inhibitor KN93 (10 μmol/L). The levels of CaMKII, p-CaMKII, CREB, p-CREB, HIF-1α, and VEGF proteins were measured with Western blotting, while HIF-1á and VEGF mRNA levels were determined using real-time RT-PCR.
Objective: To study the clinical significance of matrix metalloproteinase-9 (MMP-9), tissue inhibitor of metalloproteinases (TIMPs) and transforming growth factor beta 1 (TGF-beta1) in the serum of patients with rheumatoid arthritis (RA) associated interstitial lung disease (ILD).
Methods: Twenty-nine patients with RA only (the RA group) and 28 patients with RA associated ILD (the RA-ILD group) were included in the study. Patients in the RA-ILD group were divided into 2 subgroups, 16 in the early RA-ILD group and 12 in the late RA-ILD group.