[The genetic characteristics analysis of fusion gene of 13 strains measles viruses in China].

Objective: To study genetic characteristics of fusion gene (F gene) of H1 genotype of wild measles virus circulated in China from 1999 to 2003.

Method: 13 H1 genotype representative strains including 8 subgenotype H1a strains and 5 subgenotype H1b strains isolated in mainland China during 1999-2003 were selected. Entire F gene were amplified by reverse transcript-polymerase chain reaction and sequenced, then they were compared with the nucleotide acid sequences of Chinese measles vaccine strains and the representative strains of A, D3, D6, D7 and E genotypes from other countries.