Analysis of risk factors leading to multiple breast abscesses during lactation.

We investigated 1805 cases of breast abscesses during lactation to estimate the risk factors for multiple breast abscesses during lactation. A total of 2000 cases of breast abscesses during lactation were investigated using an online questionnaire, and 1805 cases with complete data were analyzed. The survey response rate was 90%.

Neuroprotective Effects of Sodium Butyrate and Monomethyl Fumarate Treatment through GPR109A Modulation and Intestinal Barrier Restoration on PD Mice.

Research has connected Parkinson's disease (PD) with impaired intestinal barrier. The activation of G-protein-coupled receptor 109A (GPR109A) protects the intestinal barrier by inhibiting the NF-κB signaling pathway. Sodium butyrate (NaB), which is a GPR109A ligand, may have anti-PD effects.

Heat strain in chemical protective clothing in hot-humid environment: Effects of clothing thermal properties.

Heat strain experienced by individuals wearing chemical protective clothing (CPC) is severe and dangerous especially in hot-humid environment. The development of material science and interdisciplinary studies including ergonomics, physiology and heat transfer is urgently required for the reduction of heat strain. The aim of this paper was to study the relationship among clothing thermal properties, physiological responses and environmental conditions.

Photocrosslinking silver nanoparticles-aloe vera-silk fibroin composite hydrogel for treatment of full-thickness cutaneous wounds.

Damage to the skin causes physiological and functional issues. The most effective treatment approach is the use of wound dressings. Silk fibroin (SF) is a promising candidate biomaterial for regulating wound healing; however, its antibacterial properties and biological activity must be further improved.

Granulomatous mastitis in multiparae during pregnancy and lactation: Observational study (STROBE compliant).

The incidence of granulomatous mastitis (GLM) in multiparae as seriously affected the quality of life and breastfeeding of pregnant women after delivery, but the treatment is rarely reported. In this article, the development, healing, and lactation of 13 cases were reported and a retrospective analysis was performed. 10 cases of GLM were treated at the Breast Disease Prevention and Treatment Center of Haidian Maternal & Child Health Hospital of Beijing and 3 cases of GLM were treated in the Breast Department of Weihai Municipal Hospital of Shandong province from February 2017 to May 2019.

Potential roles of gut microbiota and microbial metabolites in Parkinson's disease.

Parkinson's disease (PD) is a complicated neurodegenerative disease attributed to multifactorial changes. However, its pathological mechanism remains undetermined. Accumulating evidence has revealed the emerging functions of gut microbiota and microbial metabolites, which can affect both the enteric nervous system and the central nervous system via the microbiota-gut-brain axis.

Lactational Breast Abscesses Caused by Methicillin-Resistant or Methicillin-Sensitive Infection and Therapeutic Effect of Ultrasound-Guided Aspiration.

We investigated whether (1) there are any differences in lactational breast abscesses between patients from whom methicillin-resistant (MRSA) and those from whom methicillin-sensitive (MSSA) were isolated from pus samples and (2) there are differences in the effects of ultrasound-guided aspiration. The clinical data of 171 patients with lactational breast abscesses treated by ultrasound-guided aspiration in Beijing from January to July 2018 were retrospectively analyzed. The patients were divided into MSSA infection ( = 132) and MRSA infection ( = 39) groups according to their bacterial culture results.

The effect of tetramethylpyrazine on hydrogen peroxide-induced oxidative damage in human umbilical vein endothelial cells.

Tetramethylpyrazine has been widely used in traditional Chinese medicine to treat cardiovascular diseases such as atherosclerosis and hypertension. The underlying mechanism of cardioprotective effects, however, remains to be elucidated. Here, using human umbilical vein endothelial cells (HUVECs), we have assessed the protective effect of tetramethylpyrazine on H(2)O(2)-induced oxidative damage.

[Study on the ultraviolet spectrum in a series of 2 (1H)-quinoxalin-2-one derivatives].

A series of 2 (1H)-quinoxalin-2-one derivatives: 1-alkyl-3-methyl-2 (1H)-quinoxalin-2-one (AMQ, alkyl = H, CH3, C2H5, n-C3H7, n-C5H11, n-C16H33) have been studied by ultraviolet spectrometry. They may be used as highly active fungicides, compounds inhibiting the growth of plants, neuroprotectant for cerebral ischemia, new fluorescent probes, selective antagonists to alpha-amino-3-hydroxy-5-methly-4-isoxazole propionic acid (AMPA) et al. Results show that as the length of the alky1 chain at the nitrogen on the 1-position increases, little changes have been found in the ultraviolet absorption spectra.