Zhongguo Shi Yan Xue Ye Xue Za Zhi
February 2024
Objective: To investigate the effects of formula combined with prednisone on immune function and the ST2/IL-33 pathway in mice with immune thrombocytopenia.
Methods: In 40 BALB/c mice, 32 were constructed as immune thrombocytopenia mouse models by antiplatelet serum injection. After successful modeling, the mice were randomly divided into model group, formula group (0.
Zhongguo Shi Yan Xue Ye Xue Za Zhi
April 2023
Objective: To investigate the effect of p-coumaric acid on apoptosis of multiple myeloma cells and its related mechanism.
Methods: Multiple myeloma cell line MM.1s cells were selected and treated with different concentrations of p-coumaric acid (0, 0.
Background: Gastric cancer (GC) has become a serious threat to people's health. Accumulative evidence reveals that dysregulation of numerous microRNAs (miRNAs) has been found during malignant formation. So far, the role of microRNA-760 (miR-760) in the development of GC is largely unknown.
View Article and Find Full Text PDFObjective: To reveal the cutoff point and influencing factors in the dynamic change in phenotypic group in patients with stable angina pectoris (SAP) after Xinxuekang capsule treatment.
Methods: Five hundred and seventy-six SAP patients were randomly assigned to receive Xinxuekang (XXK) capsules or Compound Danshen (CDS) tablets for 8 weeks. Global similarity degree analysis and nonlinear mixed effects modeling (NONMEM) were employed to reveal the cutoff points and influencing factors in dynamic changes in the SAP phenotypic group.
Zhong Xi Yi Jie He Xue Bao
December 2009
Background: Although there are some Chinese herbal medicines in treatment of constipation, but no multi-center randomized controlled trials have been carried out to prove their effectiveness.
Objective: To evaluate the safety and efficacy of Yunchang Capsule in treatment of functional constipation with deficiency of both qi and yin and internal accumulation of poisonous pathogenic factors syndrome, and to explore the clinical dosage.
Design, Setting, Participants And Interventions: A randomized, double-blinded controlled, multicenter trial was conducted.