Publications by authors named "Song-Pei Wang"
2Beta-carbomethoxy-3beta-(4-chlorophenyl)-8-(2-[(18)F]fluoroethyl)nortropane ((18)F-FECNT) is a potential dopamine transporter imaging agent. In this article, a new mesylate precursor was prepared and a one-step automated synthesis of (18)F-FECNT was developed. The mesylate precursor (4) was synthesized from 2beta-carbomethoxy-3beta-(4-chlorophenyl)tropane (1) by N-demethylation, hydroxyethylation followed by mesylation at a total yield of 47%.
View Article and Find Full Text PDF(2S,3S)-3-(4-Chloro-phen-yl)-8-methyl-tropane-2-carboxylic acid.
Acta Crystallogr Sect E Struct Rep Online
August 2008
Article Synopsis
- - The compound C(15)H(18)ClNO(2) features a tropane ring with torsion angles similar to those found in cocaine and its derivatives.
- - An intra-molecular hydrogen bond exists between the nitrogen atom in the tropane ring and the oxygen atom of a carboxyl group.
- - The crystal structure is strengthened by weak C-H⋯O interactions among molecules in the ab plane, creating a two-dimensional supramolecular network.
23-Hydroxybetulinic acid is a newly isolated derivative of betulinic acid. The agent exhibits potential anti-tumor activity and functions in this regard via apoptosis. In support of pharmacokinetic and toxicological evaluations, a new assay based on liquid chromatography/mass spectrometry (LC/MS) was developed for the quantitative analysis of 23-hydroxybetulinic acid.
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