Improved ZnWO@NiCoO core-shell nanosheet arrays with regulatory interfaces and electronic redistribution.

ZnWO@NiCoO core-shell nanosheet array composites are synthesized on nickel foam a two-step hydrothermal method. The optimal conditions, including a Ni(NO)·6HO to Co(NO)·6HO molar ratio of 2 : 1, 12 hours reaction time, and 120 °C temperature, yield a specific capacitance of 875 C g at 1 A g. The electrode also maintains 81.

Differential toxic and antiepileptic features of Vigabatrin raceme and its enantiomers.

Background: The study aimed to investigate the potential pharmacological and toxicological differences between Vigabatrin (VGB) and its enantiomers S-VGB and R-VGB. The researchers focused on the toxic effects and antiepileptic activity of these compounds in a rat model.

Methods: The epileptic rat model was established by intraperitoneal injection of kainic acid, and the antiepileptic activity of VGB, S-VGB, and VGB was observed, focusing on the improvements in seizure latency, seizure frequency and sensory, motor, learning and memory deficits in epileptic rats, as well as the hippocampal expression of key molecular associated with synaptic plasticity and the Wnt/β-catenin/GSK 3β signaling pathway.

Pharmacokinetics and tissue distribution of vigabatrin enantiomers in rats.

Purpose: To investigate the pharmacokinetics and tissue distribution of VGB racemate and its single enantiomers, and explore the potential of clinic development for single enantiomer S-VGB.

Methods: In the pharmacokinetics study, male Sprague-Dawley rats were gavaged with VGB racemate or its single enantiomers dosing 50, 100 or 200 mg/kg, and the blood samples were collected during 12 h at regular intervals. In the experiment of tissue distribution, VGB and its single enantiomers were administered intravenously dosing 200 mg/kg, and the tissues including heart, liver, spleen, lung and kidney, eyes, hippocampus, and prefrontal cortex were separated at different times.

[Effects of the Three Gorges Reservoir Operation on Vertical Distribution of Chlorophyll a and Environmental Factors in Tributaries].

The hydrodynamics and environmental factors in the Xiangxi River (XXR) and Shennong River (SNR), which are tributaries of the Three Gorges Reservoir (TGR), were monitored from July to August (the low water level period) and in October (the impoundment period) in 2018. The vertical distribution characteristics of chlorophyll a and other indicators of the two tributaries were analyzed during the different operation periods, and the factors that affected the vertical distribution in each period were discussed. The results showed that the vertical distribution of dissolved oxygen, water temperature, pH value, and chlorophyll a of the XXR and SNR during the low water level period was relatively consistent.

Arsenic Trioxide Combining Leflunomide Activates Nrf2-ARE-HO-1 Signaling Pathway and Protects Heart Xenografts.

Objective: To investigate the molecular mechanisms underlying the effects of arsenic trioxide (AsO) in combination with leflunomide on the hamster-to-rat heart xenotransplant.

Methods: Transplantation of LVG hamster hearts to Lewis rats was performed by anastomosis of vessels in the neck using end-to-end anastomosis with a non-suture cuff technique. Four groups of recipient rats (n=6 in each) were treated with normal saline (control), AsO [5 mg/(kg·day) intraperitoneally], leflunomide [5 mg/(kg·d) orally], or leflunomide [5 mg/(kg·d)+AsO [5 mg/(kg·d)] in combination.

[Distribution Characteristics and Release Fluxes of Phosphorus Forms in Xiangxi Bay Sediments in the Three Gorges Reservoir Before and After Impoundment].

The sediment storage environment in tributaries has been altered by impoundment of water in the Three Gorges Reservoir area, affecting the distribution of phosphorus forms in sediment and processes at the sediment-water interface. Through collection of sediment and overlying water samples in Xiangxi Bay in August 2016 (before impoundment) and October (after impoundment), the distribution characteristics of sedimentary phosphorus and the environmental conditions of storage before and after impoundment were analyzed. Fluxes of PO-P at the sediment-water interface were also estimated.

[Nutrient Distribution Characteristics of the Sediment-water System in the Xiangxi River During the Impoundment of TGR].

This study characterizes the nutrient distribution of the sediment-water system in the Xiangxi River (XXR) during the impoundment of the Three Gorges Reservoir (TGR). In 2016, the research group obtained samples in the Xiangxi River, analyzed the distribution of nitrogen, phosphorus, and O.M.

[Characteristics of Nitrogen Release at the Sediment-Water Interface in the Typical Tributaries of the Three Gorges Reservoir During the Sensitive Period in Spring].

Overlying water and sediment interstitial water samples were acquired to study the nitrogen release between sediments and water interfaces in Xiangxi Bay in April 2016 during the Sensitive Period in spring. The spatial distribution of different forms of nitrogen in the sediment was analyzed, the diffusion fluxes of different forms of nitrogen in the sediments and water systems were also measured, and a correlation analysis with environmental factors was conducted. The results show that overlying water and sediment interstitial water (TN) ranges from 1.

[Effect of the Rainfall on Extinction of Cyanobacteria Bloom and Its Mechanism Analysis].

There were three rainfall events with different intensity in the Xiangxi Bay (XXB) from May 24 to June 2 in 2016. The factors such as hydrodynamics, water temperature, optical properties, and chlorophyll a concentrations during the rainfall events were analyzed. During the May 27 moderate rain period, the upstream flow of the reservoir bay increased by 1.

[Characteristics of nutrient loss by runoff in sloping arable land of yellow-brown under different rainfall intensities].

In order to investigate the loss characteristics of N and P through surface flow and interflow under different rainfall intensities, a field experiment was conducted on the sloping arable land covered by typical yellow-brown soils inXiangxi River watershed by artificial rainfall. The results showed that the discharge of surface flow, total runoff and sediment increased with the increase of rain intensity, while the interflow was negatively correlated with rain intensity under the same total rainfall. TN, DN and DP were all flushed at the very beginning in surface flow underdifferent rainfall intensities; TP fluctuated and kept consistent in surface flow without obvious downtrend.

[Phosphorus output characteristics under different rainfall-runoffs in Gaolan River].

Through capturing the dynamics of water quantity and quality during varied intensities of rainfall, the variation characteristics of different forms of phosphorus and flux during the producing of runoff were studied systematically in Gaolan River watershed (a secondary tributary of Three Gorges Reservoir). Meanwhile, the phosphoric loadings from point and non-point sour,-were identified, respectively. The results show that: the variation of rainfall-runoff under " squat" rain was relatively slow, while un,c "pointed thin" rain it presented quickly both during rising and recession.