Outcome of papillary thyroid microcarcinoma: Study of 1,990 cases.

The present study examines the requirement of prophylactic neck node dissection in papillary thyroid microcarcinoma (PTMC) patients by analyzing high-risk factors of neck lymph node metastasis in PTMC. The clinical pathological data was a review of 1,990 patients diagnosed between January 2013 and January 2014. The data included information on patient gender, age, tumor size, multifocal, tumor pathological staging, bilateral thyroid cancer, the subtypes, mutation, human telomerase reverse transcriptase (), extrathyroidal invasion and neck lymph node metastasis.

[Mechanism underlying spatial vision deficit of monocular amblyopia based on the theory of Magnocellular and Parvocellular (M-P) pathways].

Objective: To investigate the relationship between the characteristics of spatial vision deficit and the degree of amblyopia in monocular amblyopes, and to analyze its mechanism with the theory of Magnocellular and Parvocellular pathways.

Methods: One hundred and eleven patients with monocular amblyopes aged 7-34 were included in this study. Distance best corrected visual acuity (BCVA) in logMAR units and contrast sensitivity function test were performed on both eyes in all patients with ETDRS digital visual chart and functional test system OPTECR 6500.

Identification of a novel frameshift mutation in PITX2 gene in a Chinese family with Axenfeld-Rieger syndrome.

Objective: Axenfeld-Rieger syndrome (ARS) is phenotypically and genetically heterogeneous. In this study, we identified the underlying genetic defect in a Chinese family with ARS.

Methods: A detailed family history and clinical data were recorded.

[Harmonic scalpel versus conventional resection in thyroid surgery: a meta analysis on the safety outcomes].

Objective: To compare the safety between harmonic scalpel and conventional resection in total or near total thyroidectomy with meta-analysis.

Methods: The prospective randomized controlled studies were searched for in electronic databases (MEDLINE, EMBASE, Cochrane Library). Meta analysis of acquired data was performed through the use of RevMan 5.

[Study of the visual deficits pattern in strabismic and anisometropic amblyopia].

Objective: To elucidate the difference in the pathogenesis between strabismic and anisometropic amblyopia.

Methods: It was a case-control study.We used psychophysical methods, including grating acuity, edge contrast sensitivity, contrast sensitivity function tests, and examined the visual functions of 150 cases from 8 to 40-year-old.

Anisometropia magnitude and visual deficits in previously untreated anisometropic amblyopia.

Aim: To assess the quantitative association between anisometropia magnitude and the losses of resolution and contrast sensitivity; and to exemplify how the function of fusion and stereopsis vary with anisometropia magnitude (AM) in previously untreated anisometropic amblyopes.

Methods: A total of 57 patients with previously untreated anisometropic amblyopia without strabismus (range: 8-35 years), were measured refractive error, best corrected visual acuity (BCVA), fusion and stereopsis, and 48 patients have completed contrast sensitivity function test. AM was determined by dioptric vector addition model, and the amblyopia depth was determined by the difference of BCVA in logMAR units between the amblyopic and fellow eyes.

Novel mutation c.980_983delATTA compound with c.986C>A mutation of the FRMD7 gene in a Chinese family with X-linked idiopathic congenital nystagmus.

Objective: To screen mutations in FERM domain-containing protein 7 (FRMD7) gene in two Chinese families with X-linked idiopathic congenital nystagmus (XLICN).

Methods: Common ophthalmic data and peripheral blood of two Chinese XLICN families (families A and B) were collected after informed consent. Genomic DNA was prepared from the peripheral blood of members of the two families and from 100 normal controls.

Progression of solitary and multifocal papillary thyroid carcinoma - a retrospective study of 368 patients.

Background: Papillary thyroid carcinoma (PTC) represents one of the most frequent endocrine malignancies. Several factors have been found to be involved in determining the outcome of treatment for patients with PTC. Large tumor size, diagnosis at an early age, extra-thyroidal invasion, aggressive histological variants, and distant metastases are the most important determinants of a poor outcome.

[Biological characteristics and management of familial papillary thyroid carcinoma].

Objective: To analyze the clinical biological characteristics and investigate the managements of familial papillary thyroid carcinoma (FPTC).

Methods: Clinical data of 36 patients with PTC from 15 families were retrospectively analyzed compared with 95 control cases taken randomly from the patients with sporadic PTC diagnosed and treated in Tianjin Cancer Hospital between January 2010 and August 2011.

Results: Of the 36 patients with FPTC, 15 (41.

[Analysis of variation trends of thyroid cancer treated in Tianjin Cancer Hospital form 1954 to 2009].

Objective: To investigate and analyze the variation trends in the pathological composition of thyroid cancer patients treated in Tianjin Cancer Hospital from 1954 to 2009.

Methods: To retrospectively analyze the incidence and clinical features of different pathological types of thyroid cancers in 4342 patients between different time periods from 1954 to 2009.

Results: In the four main pathological types of thyroid cancers, the component ratio of papillary thyroid cancer in every period was 68.